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Q8YPT4 (RNC2_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3 2
EC=3.1.26.3
Alternative name(s):
Ribonuclease III 2
Short name=RNase III 2
Gene names
Name:rnc2
Ordered Locus Names:all4107
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Sequence caution

The sequence BAB75806.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 242242Ribonuclease 3 2 HAMAP-Rule MF_00104
PRO_0000416610

Regions

Domain12 – 137126RNase III
Domain165 – 23571DRBM

Sites

Active site551 Potential
Active site1261 By similarity
Metal binding511Magnesium By similarity
Metal binding1231Magnesium By similarity
Metal binding1261Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YPT4 [UniParc].

Last modified April 18, 2012. Version 2.
Checksum: 9DF81DA20D1CA37F

FASTA24227,052
        10         20         30         40         50         60 
MTLVYPRRQR QLESLVRKLG LPITAPIKWE LLDLALTHPT VSESANYEQL EFVGDAVVRL 

        70         80         90        100        110        120 
AAAVMLWETY PDCPVGDFAA IRSVLVSDRI LAQLAREYGL ELHLLVAGSA TSDKIGQESR 

       130        140        150        160        170        180 
LADAFEAVLG ALYLSTSNLE LIRPWLDHHF RQLAAEIRLD PARLNYKAAL QEWTQAQFKV 

       190        200        210        220        230        240 
LPEYRVVEIN QANRTQERFA AEVWLHGNKL GEGKGRSIKA AEQAAAKVAF LAITPPEEIA 


NQ

« Hide

References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000019 Genomic DNA. Translation: BAB75806.1. Different initiation.
PIRAD2319.
RefSeqNP_488147.1. NC_003272.1.

3D structure databases

HSSPHSSP built from PDB template 1O0W based on UniProtKB Q9X0I6.
ModBaseSearch...

Protein-protein interaction databases

STRING103690.all4107.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB75806; BAB75806; BAB75806.
GeneID1107708.
KEGGana:all4107.
PATRIC22778761. VBINosSp37423_4829.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
ProtClustDBCLSK379325.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC2_NOSS1
AccessionPrimary (citable) accession number: Q8YPT4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: April 18, 2012
Last modified: May 1, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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