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Q8YPR1 (PGK_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:all4131
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Mass spectrometry

Molecular mass is 42472 Da from positions 1 - 400. Determined by MALDI. Ref.2

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145897

Regions

Nucleotide binding356 – 3594ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1211Substrate By similarity
Binding site1541Substrate By similarity
Binding site2051ATP By similarity
Binding site2961ATP; via carbonyl oxygen By similarity
Binding site3271ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YPR1 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: FA9EBE9015D4C0F9

FASTA40042,441
        10         20         30         40         50         60 
MSKKTVASLS AADISGKRAL VRVDFNVPLD DQGNITDDTR IRAALPTIQD LTQKGAKVIL 

        70         80         90        100        110        120 
ASHFGRPKGV DEKLRLTPVA KRLSELLGQE VIKTDDSIGD EVAAKVATLQ NGQVLLLENV 

       130        140        150        160        170        180 
RFYKEEEKND PEFAKKLAAN ADFYVNDAFG TAHRAHASTE GVTKFLSPSV AGYLVEKELQ 

       190        200        210        220        230        240 
YLQSAIENPQ RPLAAIIGGS KVSSKIGVIE TLLEKCDKLI IGGGMIFTFY KARGLNVGKS 

       250        260        270        280        290        300 
LVEEDKLELA KSLEAKAKER GVSLLLPTDV VLADNFAPDA NSQTVSIENI PDGWMGLDIG 

       310        320        330        340        350        360 
PDSVKVFQAA LADTKTVIWN GPMGVFEFDK FAAGTEAIAH TLAEIGKTGT TTIIGGGDSV 

       370        380        390        400 
AAVEKVGLAD QMSHISTGGG ASLELLEGKV LPGIAALDEA 

« Hide

References

« Hide 'large scale' references
[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.
[2]Singh H., Rajaram H., Apte S.K.
Submitted (DEC-2008) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 306-315, MASS SPECTROMETRY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000019 Genomic DNA. Translation: BAB75830.1.
PIRAD2322.
RefSeqNP_488171.1. NC_003272.1.

3D structure databases

ProteinModelPortalQ8YPR1.
SMRQ8YPR1. Positions 1-399.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING103690.all4131.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB75830; BAB75830; BAB75830.
GeneID1107733.
KEGGana:all4131.
PATRIC22778815. VBINosSp37423_4856.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAPGIACIS.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_NOSS1
AccessionPrimary (citable) accession number: Q8YPR1
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: March 1, 2002
Last modified: June 11, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways