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Q8YNF7 (GCST_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aminomethyltransferase
EC=2.1.2.10
Alternative name(s):
Glycine cleavage system T protein
Gene names
Name:gcvT
Ordered Locus Names:all4609
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity. HAMAP MF_00259

Catalytic activity

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Sequence similarities

Belongs to the GcvT family.

Ontologies

Keywords
   Molecular functionAminotransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycine catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular functionaminomethyltransferase activity

Inferred from electronic annotation. Source: EC

transaminase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 376376Aminomethyltransferase HAMAP MF_00259
PRO_0000122533

Sequences

Sequence LengthMass (Da)Tools
Q8YNF7 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 3369E744CFF6CADA

FASTA37640,775
        10         20         30         40         50         60 
MANQKDTAET LARTPLYQLG VELKARLTSF GGWEMPVQFS GITREHEAVR NAAGMFDISH 

        70         80         90        100        110        120 
MGKFTLQGKN LISQLQGLVP SDLSRLQPGQ AQYTVLLNPQ GGIIDDIIVY YQGEDNTGTQ 

       130        140        150        160        170        180 
QAFIIVNAAT TSKDKAWILS HLDQNQVQFQ DISPAKVLIA IQGPKAIGYL QPFVQQNLQP 

       190        200        210        220        230        240 
IKAFGHLEAT VLGQAGFIAR TGYTGEDGFE ILVDPEVGVE LWRSLYDAGV IPCGLGARDT 

       250        260        270        280        290        300 
LRLEAAMALY GQDIDDNTTP LEAGLGWLVH LDTKGDFIGR SVLEQQKATG VQRRLIGLQT 

       310        320        330        340        350        360 
QGRNIARHGY QVLSDGKVVG GVTSGTLSPT LGYPVALAYV PSKLAKVGQP LEVEIRGKAY 

       370 
PAVVVKRPFY RSSNKG

« Hide

References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000019 Genomic DNA. Translation: BAB76308.1.
PIRAI2381.
RefSeqNP_488649.1. NC_003272.1.

3D structure databases

ProteinModelPortalQ8YNF7.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ8YNF7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1108210.
GenomeReviewsGene locus all4609 in contig BA000019_GR.
KEGGana:all4609.
NMPDRfig|103690.1.peg.4916.
PATRIC22779836. VBINosSp37423_5364.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0404.
HOGENOMHBG299834.
OMAKALYGGM.
PhylomeDBQ8YNF7.
ProtClustDBPRK00389.

Enzyme and pathway databases

BioCycNSP103690:ALL4609-MONOMER.

Family and domain databases

HAMAPMF_00259. GcvT.
[Tree]
InterProIPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR006223. GcvT.
IPR022903. NH2_Me_Trfase.
[Graphical view]
KOK00605.
PANTHERPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFPIRSF006487. GcvT. 1 hit.
TIGRFAMsTIGR00528. GcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGCST_NOSS1
AccessionPrimary (citable) accession number: Q8YNF7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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