Reviewed, UniProtKB/Swiss-Prot Q8YN19 (PPNK1_ANASP)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 1
      Short name=Poly(P)/ATP NAD kinase 1
    EC=2.7.1.23

Gene names

Name:	ppnK1
Ordered Locus Names:	all4751

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361		PRO_0000120588

Sequences

	Sequence		Length	Mass (Da)
	Q8YN19-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 028A0D2F3E2A9271	FASTA	305	32,798
	10 20 30 40 50 60 MPKVGIIYND IKPVAGRVAI ELKDKLTAAG WDVSITSSIG GILGYSNPES PVCHTPIDGL 70 80 90 100 110 120 TPPGFDSEMK FAIVLGGDGT VLAASRQVAP CGIPILAINT GHMGFLTETY LNQLPQAIDQ 130 140 150 160 170 180 AIAGEYEIEE RAMLTVKVLR GESVLWEALC LNEMVLHREP LTSMCHFEIA VGRHAPVDIA 190 200 210 220 230 240 ADGVIVSTPT GSTAYSLSAG GPVVAPGVPV LQLVPICPHS LASRALVFPD TEPVNIYPVN 250 260 270 280 290 300 IPRLVMVVDG NGGCYIFPED RVYLERSPYS VKFIRLQPPE FFRILREKLG WGLPHIAKPT SVELP

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000019 Genomic DNA. Translation: BAB76450.1.
PIR	AG2399.
RefSeq	NP_488791.1.
3D structure databases
SMR	Q8YN19. Positions 2-293.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8YN19.
Genome annotation databases
GeneID	1108352.
GenomeReviews	Gene locus all4751 in contig BA000019_GR.
KEGG	ana:all4751.
NMPDR	fig|103690.1.peg.5058.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	LNEMVLH.
PhylomeDB	Q8YN19.
Enzyme and pathway databases
BioCyc	NSP103690:ALL4751-MONOMER.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK1_ANASP

Accession

Primary (citable) accession number: Q8YN19

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2002
Last sequence update:	March 1, 2002
Last modified:	January 19, 2010
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)