Reviewed, UniProtKB/Swiss-Prot Q8YMT3 (SURE_ANASP)

Names and origin

Protein names

Recommended name:
    5'-nucleotidase surE
    EC=3.1.3.5
Alternative name(s):
    Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	alr4846

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity.
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 265	265	5'-nucleotidase surE HAMAP MF_00060		PRO_0000111787
Sites
	Metal binding	8	1	Divalent metal cation By similarity
	Metal binding	9	1	Divalent metal cation By similarity
	Metal binding	40	1	Divalent metal cation By similarity
	Metal binding	98	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8YMT3-1 [UniParc]. Last modified March 5, 2002. Version 1. Checksum: 9855CE04B5ED61E8	FASTA	265	28,962
	10 20 30 40 50 60 MKLLISNDDG ISALGIRTLA NALAEAGHDV TVVCPDRERS ATGHGLTLHQ PIRAEIVESI 70 80 90 100 110 120 FHPAIKAWAC DGTPSDCVKL ALWALLESPP DLVLSGINQG ANLGTEILYS GTVSAAMEGM 130 140 150 160 170 180 IEGIPSIAFS LTSHISRNFQ PAAKFATILV EQLAAKPIPD LMLLNVNIPP VEWEEIAGVK 190 200 210 220 230 240 LTRQGVRRYV DVFDKRTDPR GKTYYWLTGE VLEEVEPPEG LNLPQNVPID VHVVRNNYIS 250 260 ITPLQYNLTY ATGIDKLSDW DFPLS

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000019 Genomic DNA. Translation: BAB76545.1.
PIR	AF2411.
RefSeq	NP_488886.1.
3D structure databases
HSSP	HSSP built from PDB template 1J9L based on UniProtKB P96112.
ModBase	Search...
Genome annotation databases
GeneID	1108447.
GenomeReviews	Gene locus alr4846 in contig BA000019_GR.
KEGG	ana:alr4846.
NMPDR	fig|103690.1.peg.5153.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8YMT3.
OMA	Q8YMT3. NLNIPPC.
Enzyme and pathway databases
BioCyc	NSP103690:ALR4846-MON.
Family and domain databases
HAMAP	MF_00060. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
ProDom	PD005378. SurE. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00087. surE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_ANASP

Accession

Primary (citable) accession number: Q8YMT3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	March 5, 2002
Last modified:	June 16, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)