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Q8YM77 (NADD_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable nicotinate-nucleotide adenylyltransferase

EC=2.7.7.18
Alternative name(s):
Deamido-NAD(+) diphosphorylase
Deamido-NAD(+) pyrophosphorylase
Nicotinate mononucleotide adenylyltransferase
Short name=NaMN adenylyltransferase
Gene names
Name:nadD
Ordered Locus Names:all5063
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) By similarity. HAMAP-Rule MF_00244

Catalytic activity

ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+. HAMAP-Rule MF_00244

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1. HAMAP-Rule MF_00244

Sequence similarities

Belongs to the NadD family.

Ontologies

Keywords
   Biological processPyridine nucleotide biosynthesis
   LigandATP-binding
NAD
Nucleotide-binding
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processNAD biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

nicotinate-nucleotide adenylyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208Probable nicotinate-nucleotide adenylyltransferase HAMAP-Rule MF_00244
PRO_0000181377

Sequences

Sequence LengthMass (Da)Tools
Q8YM77 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: BBEFABE0EF995510

FASTA20823,745
        10         20         30         40         50         60 
MQHLAVFGGT FDPIHWGHLL IAEAALQQIP IEKVIWVPSL NPPHKKASAF RHRLAMLQLA 

        70         80         90        100        110        120 
TQDNPAFTVS SVEKNRSGVS YAINTLTDLS VCFPNTHWYW IVGLDTFQTL PRWYRGQELA 

       130        140        150        160        170        180 
PMCDWLIAPR LVGGENIAQS ELICKQVKQQ LRKQSDTIHW HLLHIPLVGV SSSLIRKLYR 

       190        200 
IGKSIRYLVP EDVRSYIAAH KLYSEDSE 

« Hide

References

[1]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000019 Genomic DNA. Translation: BAB76762.1.
PIRAG2438.
RefSeqNP_489103.1. NC_003272.1.

3D structure databases

ProteinModelPortalQ8YM77.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING103690.all5063.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB76762; BAB76762; BAB76762.
GeneID1108667.
KEGGana:all5063.
PATRIC22780817. VBINosSp37423_5848.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1057.
HOGENOMHOG000262780.
KOK00969.
OMAHLIMAQY.
OrthoDBEOG6F55KJ.
ProtClustDBCLSK286670.

Enzyme and pathway databases

UniPathwayUPA00253; UER00332.

Family and domain databases

Gene3D3.40.50.620. 1 hit.
HAMAPMF_00244. NaMN_adenylyltr.
InterProIPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR12039. PTHR12039. 1 hit.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNADD_NOSS1
AccessionPrimary (citable) accession number: Q8YM77
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: March 1, 2002
Last modified: February 19, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways