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Q8YM77

- NADD_NOSS1

UniProt

Q8YM77 - NADD_NOSS1

Protein

Probable nicotinate-nucleotide adenylyltransferase

Gene

nadD

Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).UniRule annotation

    Catalytic activityi

    ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. nicotinate-nucleotide adenylyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Nucleotidyltransferase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Keywords - Ligandi

    ATP-binding, NAD, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00253; UER00332.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable nicotinate-nucleotide adenylyltransferaseUniRule annotation (EC:2.7.7.18UniRule annotation)
    Alternative name(s):
    Deamido-NAD(+) diphosphorylaseUniRule annotation
    Deamido-NAD(+) pyrophosphorylaseUniRule annotation
    Nicotinate mononucleotide adenylyltransferaseUniRule annotation
    Short name:
    NaMN adenylyltransferaseUniRule annotation
    Gene namesi
    Name:nadDUniRule annotation
    Ordered Locus Names:all5063
    OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
    Taxonomic identifieri103690 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
    ProteomesiUP000002483: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 208208Probable nicotinate-nucleotide adenylyltransferasePRO_0000181377Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi103690.all5063.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YM77.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NadD family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1057.
    HOGENOMiHOG000262780.
    KOiK00969.
    OMAiHPENDYY.
    OrthoDBiEOG6F55KJ.

    Family and domain databases

    Gene3Di3.40.50.620. 1 hit.
    HAMAPiMF_00244. NaMN_adenylyltr.
    InterProiIPR004821. Cyt_trans-like.
    IPR005248. NAMN_adtrnsfrase.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR12039. PTHR12039. 1 hit.
    PfamiPF01467. CTP_transf_2. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.
    TIGR00482. TIGR00482. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8YM77-1 [UniParc]FASTAAdd to Basket

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    MQHLAVFGGT FDPIHWGHLL IAEAALQQIP IEKVIWVPSL NPPHKKASAF    50
    RHRLAMLQLA TQDNPAFTVS SVEKNRSGVS YAINTLTDLS VCFPNTHWYW 100
    IVGLDTFQTL PRWYRGQELA PMCDWLIAPR LVGGENIAQS ELICKQVKQQ 150
    LRKQSDTIHW HLLHIPLVGV SSSLIRKLYR IGKSIRYLVP EDVRSYIAAH 200
    KLYSEDSE 208
    Length:208
    Mass (Da):23,745
    Last modified:March 1, 2002 - v1
    Checksum:iBBEFABE0EF995510
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000019 Genomic DNA. Translation: BAB76762.1.
    PIRiAG2438.
    RefSeqiNP_489103.1. NC_003272.1.
    WP_010999189.1. NC_003272.1.

    Genome annotation databases

    EnsemblBacteriaiBAB76762; BAB76762; BAB76762.
    GeneIDi1108667.
    KEGGiana:all5063.
    PATRICi22780817. VBINosSp37423_5848.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000019 Genomic DNA. Translation: BAB76762.1 .
    PIRi AG2438.
    RefSeqi NP_489103.1. NC_003272.1.
    WP_010999189.1. NC_003272.1.

    3D structure databases

    ProteinModelPortali Q8YM77.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 103690.all5063.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB76762 ; BAB76762 ; BAB76762 .
    GeneIDi 1108667.
    KEGGi ana:all5063.
    PATRICi 22780817. VBINosSp37423_5848.

    Phylogenomic databases

    eggNOGi COG1057.
    HOGENOMi HOG000262780.
    KOi K00969.
    OMAi HPENDYY.
    OrthoDBi EOG6F55KJ.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00332 .

    Family and domain databases

    Gene3Di 3.40.50.620. 1 hit.
    HAMAPi MF_00244. NaMN_adenylyltr.
    InterProi IPR004821. Cyt_trans-like.
    IPR005248. NAMN_adtrnsfrase.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR12039. PTHR12039. 1 hit.
    Pfami PF01467. CTP_transf_2. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00125. cyt_tran_rel. 1 hit.
    TIGR00482. TIGR00482. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 7120 / UTEX 2576.

    Entry informationi

    Entry nameiNADD_NOSS1
    AccessioniPrimary (citable) accession number: Q8YM77
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 11, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3