Reviewed, UniProtKB/Swiss-Prot Q8YM52 (NTPA_ANASP)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase

Gene names

Ordered Locus Names:

all5088

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	196 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H(2)O = NDP + phosphate.
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 196	196	Nucleoside-triphosphatase		PRO_0000178116

Sequences

	Sequence		Length	Mass (Da)
	Q8YM52-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 1A85738A1CDE2558	FASTA	196	20,883
	10 20 30 40 50 60 MTKILIVATS NAGKLREMQA YLANTDWELT LKPTELEVEE TGDTFASNAC LKASEVAKAT 70 80 90 100 110 120 GNWAIADDSG LQVDALNGLP GVYSARYGKT DGERISRLLK ELGSEVNRQA QFVCVVAIAS 130 140 150 160 170 180 PDGAIALQAE GICRGEILHA PLGSGGFGYD PIFYVPEKQL TFAEMTPELK KSVSHRGKAF 190 AALLPKMAAM LSSSAE

References

[1]

"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000019 Genomic DNA. Translation: BAB76787.1.
PIR	AH2441.
RefSeq	NP_489128.1.
3D structure databases
HSSP	HSSP built from PDB template 1B78 based on UniProtKB Q57679.
ModBase	Search...
Genome annotation databases
GeneID	1108692.
GenomeReviews	Gene locus all5088 in contig BA000019_GR.
KEGG	ana:all5088.
NMPDR	fig|103690.1.peg.5395.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8YM52.
Enzyme and pathway databases
BioCyc	NSP103690:ALL5088-MON.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p_like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
TIGRFAMs	TIGR00042. Ham1p_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NTPA_ANASP

Accession

Primary (citable) accession number: Q8YM52

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2002
Last sequence update:	March 1, 2002
Last modified:	July 22, 2008
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)