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Protein

Phycocyanobilin lyase CpcT

Gene

cpcT1

Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalyzes the site-selective attachment of phycocyanobilin (PCB) to 'Cys-154' of C-phycocyanin subunit beta (CpcB) and to 'Cys-153' of phycoerythrocyanin subunit beta (PecB). Does not have chromophore lyase activity for ApcA1, ApcA2, ApcB, ApcD, ApcF or PecA.1 Publication

GO - Molecular functioni

GO - Biological processi

  • protein-phycocyanobilin linkage Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Names & Taxonomyi

Protein namesi
Recommended name:
Phycocyanobilin lyase CpcT (EC:4.-.-.-)
Gene namesi
Name:cpcT1
Synonyms:cpeT1
Ordered Locus Names:all5339
OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199Phycocyanobilin lyase CpcTPRO_0000403160Add
BLAST

Expressioni

Inductioni

Constitutively expressed.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi103690.all5339.

Structurei

Secondary structure

1
199
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi7 – 148Combined sources
Beta strandi16 – 194Combined sources
Helixi21 – 266Combined sources
Beta strandi34 – 407Combined sources
Turni43 – 475Combined sources
Beta strandi48 – 5710Combined sources
Beta strandi65 – 7511Combined sources
Beta strandi78 – 869Combined sources
Helixi89 – 924Combined sources
Helixi95 – 973Combined sources
Helixi99 – 1024Combined sources
Helixi107 – 1093Combined sources
Beta strandi110 – 1123Combined sources
Beta strandi118 – 1225Combined sources
Beta strandi124 – 1318Combined sources
Beta strandi133 – 1353Combined sources
Beta strandi138 – 1414Combined sources
Beta strandi144 – 1485Combined sources
Beta strandi151 – 1544Combined sources
Beta strandi159 – 1624Combined sources
Beta strandi164 – 1674Combined sources
Turni168 – 1703Combined sources
Beta strandi173 – 1764Combined sources
Beta strandi178 – 1803Combined sources
Beta strandi182 – 1898Combined sources
Helixi191 – 1933Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4O4OX-ray1.95A/B1-199[»]
4O4SX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L1-199[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CpcT/CpeT biliprotein lyase family.Curated

Phylogenomic databases

eggNOGiENOG4108SMZ. Bacteria.
ENOG4111FSP. LUCA.
HOGENOMiHOG000233426.
OMAiAHIRVCM.
OrthoDBiEOG61041S.

Family and domain databases

HAMAPiMF_01460. Chrphore_lyase_CpxT.
InterProiIPR010404. CpcT/CpeT.
[Graphical view]
PfamiPF06206. CpeT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YLF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHSTDIATL ARWMAADFSN QAQAFENPPF YAHIRVCMRP LPWEVLSGVG
60 70 80 90 100
FFVEQAYDYM LNDPYRLRVL KLMIVGDRIH IENYTVKQEE NFYGASRDLN
110 120 130 140 150
RLQTLTSESL EKLPGCNMIV EWTGNSFKGT VEPGKGCIVV RKGQKTYLDS
160 170 180 190
EFEINEEKFI SLDRGRDLET DAHIWGSVAG PFYFVRLHNF ADEVKISAE
Length:199
Mass (Da):22,870
Last modified:March 1, 2002 - v1
Checksum:i144FFBFD85065AA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB77038.1.
PIRiAC2473.
RefSeqiWP_010999463.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB77038; BAB77038; BAB77038.
KEGGiana:all5339.
PATRICi22781415. VBINosSp37423_6143.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000019 Genomic DNA. Translation: BAB77038.1.
PIRiAC2473.
RefSeqiWP_010999463.1. NC_003272.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4O4OX-ray1.95A/B1-199[»]
4O4SX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L1-199[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi103690.all5339.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB77038; BAB77038; BAB77038.
KEGGiana:all5339.
PATRICi22781415. VBINosSp37423_6143.

Phylogenomic databases

eggNOGiENOG4108SMZ. Bacteria.
ENOG4111FSP. LUCA.
HOGENOMiHOG000233426.
OMAiAHIRVCM.
OrthoDBiEOG61041S.

Family and domain databases

HAMAPiMF_01460. Chrphore_lyase_CpxT.
InterProiIPR010404. CpcT/CpeT.
[Graphical view]
PfamiPF06206. CpeT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7120 / UTEX 2576.
  2. "Lyase activities of CpcS- and CpcT-like proteins from Nostoc PCC7120 and sequential reconstitution of binding sites of phycoerythrocyanin and phycocyanin beta-subunits."
    Zhao K.H., Zhang J., Tu J.M., Bohm S., Ploscher M., Eichacker L., Bubenzer C., Scheer H., Wang X., Zhou M.
    J. Biol. Chem. 282:34093-34103(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION AS A CHROMOPHORE LYASE, INDUCTION.
    Strain: PCC 7120 / UTEX 2576.
  3. "Phycobilin:cystein-84 biliprotein lyase, a near-universal lyase for cysteine-84-binding sites in cyanobacterial phycobiliproteins."
    Zhao K.H., Su P., Tu J.M., Wang X., Liu H., Ploscher M., Eichacker L., Yang B., Zhou M., Scheer H.
    Proc. Natl. Acad. Sci. U.S.A. 104:14300-14305(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBSTRATE SPECIFICITY.
    Strain: PCC 7120 / UTEX 2576.

Entry informationi

Entry nameiCPCT_NOSS1
AccessioniPrimary (citable) accession number: Q8YLF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: March 1, 2002
Last modified: December 9, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.