Reviewed, UniProtKB/Swiss-Prot Q8YJI8 (QUEC_BRUME)

Names and origin

Protein names

Recommended name:
    Queuosine biosynthesis protein queC
    EC=3.5.-.-

Gene names

Name:	queC
Ordered Locus Names:	BMEI0095

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0) By similarity.
Pathway	Purine metabolism; 7-cyano-7-deazaguanine biosynthesis. HAMAP MF_01633
Sequence similarities	Belongs to the queC family.

Ontologies

Keywords
Biological process	Queuosine biosynthesis
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	queuosine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Queuosine biosynthesis protein queC HAMAP MF_01633		PRO_0000246815

Sequences

	Sequence		Length	Mass (Da)
	Q8YJI8-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 0309DDFBB3468597	FASTA	232	25,256
	10 20 30 40 50 60 MKTLVICSGG LDSVSLAHKM AAEHELTGLL SFDYGQRHKK ELDFAQACAK RLGVPHQIID 70 80 90 100 110 120 IRTIGASLTG SALTDDVDVP DGHYAEETMK VTVVPNRNAI MLAIAFGVAA AQKADAVALA 130 140 150 160 170 180 VHGGDHFIYP DCRPGFIEAF QTMQKHALDG YADVKLLAPY VHATKADIVA DGAKYRTPFE 190 200 210 220 230 ATWSCYKGAD RHCGRCGTCV ERREAFHLAG IDDPTSYEDA DFWRATTQKR NA

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008917 Genomic DNA. Translation: AAL51277.1.
PIR	AB3264.
RefSeq	NP_539013.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1195807.
GenomeReviews	Gene locus BMEI0095 in contig AE008917_GR.
KEGG	bme:BMEI0095.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG553284.
OMA	YPDCRPD.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0095-MON.
Family and domain databases
HAMAP	MF_01633. [Tree]
InterPro	IPR004479. ExsB/QueC. IPR018317. Queuosine_synth-like. [Graphical view]
Pfam	PF06508. ExsB. 1 hit. [Graphical view]
PIRSF	PIRSF006293. ExsB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

QUEC_BRUME

Accession

Primary (citable) accession number: Q8YJI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 25, 2006
Last sequence update:	March 1, 2002
Last modified:	December 15, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)