Reviewed, UniProtKB/Swiss-Prot Q8YJF3 (ISPZ_BRUME)

Names and origin

Protein names

Recommended name:
    Probable intracellular septation protein

Gene names

Name:	ispZ
Ordered Locus Names:	BMEI0130

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Involved in cell division; probably involved in intracellular septation By similarity.
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the ispZ family.

Ontologies

Keywords
Biological process	Cell cycle Cell division Septation
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	barrier septum formation Inferred from electronic annotation. Source: HAMAP cell cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 200	200	Probable intracellular septation protein HAMAP MF_00189		PRO_0000206525
Regions
	Transmembrane	1 – 21	21	Potential
	Transmembrane	37 – 57	21	Potential
	Transmembrane	66 – 86	21	Potential
	Transmembrane	103 – 123	21	Potential
	Transmembrane	136 – 156	21	Potential
	Transmembrane	167 – 187	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8YJF3-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 04A1E42F3418A8F0	FASTA	200	22,330
	10 20 30 40 50 60 MPPLLKLALE LGPLLVFFFA NARGEMLIER FPILGSIGAP IFLATALFMA ATVIALAISW 70 80 90 100 110 120 SMTRTLAIMP LVSGIVVLVF GALTLWLHND TFIKMKPTIV NTLFGGILLG GLFFGKSLLG 130 140 150 160 170 180 YVFDSAFRLD AEGWRKLTLR WGLFFIFLAI VNEIVWRNFS TDTWVSFKVW GIMPITIVFT 190 200 LLQMPLIQKH SLTDEENTAS

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008917 Genomic DNA. Translation: AAL51312.1.
PIR	AE3268.
RefSeq	NP_539048.2.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1195842.
GenomeReviews	Gene locus BMEI0130 in contig AE008917_GR.
KEGG	bme:BMEI0130.
NMPDR	fig|224914.1.peg.130.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8YJF3.
OMA	KVTIVYA
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0130-MON.
Family and domain databases
HAMAP	MF_00189. [Tree]
InterPro	IPR006008. Intracell_sepatation_prot_A. [Graphical view]
Pfam	PF04279. IspA. 1 hit. [Graphical view]
TIGRFAMs	TIGR00997. ispZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ISPZ_BRUME

Accession

Primary (citable) accession number: Q8YJF3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 28, 2003
Last sequence update:	March 1, 2002
Last modified:	November 24, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)