Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8YJ95

- RF1_BRUME

UniProt

Q8YJ95 - RF1_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peptide chain release factor 1

Gene

prfA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.UniRule annotation

GO - Molecular functioni

  1. translation release factor activity, codon specific Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 1UniRule annotation
Short name:
RF-1UniRule annotation
Gene namesi
Name:prfAUniRule annotation
Ordered Locus Names:BMEI0191
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 359359Peptide chain release factor 1PRO_0000177644Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei235 – 2351N5-methylglutamineUniRule annotation

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF1.UniRule annotation

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEI0191.

Structurei

3D structure databases

ProteinModelPortaliQ8YJ95.
SMRiQ8YJ95. Positions 68-355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic/mitochondrial release factor family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000074815.
KOiK02835.
OMAiNDINDRE.
OrthoDBiEOG6TN48J.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00093. Rel_fac_1.
InterProiIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00019. prfA. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YJ95-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIALPQDRMD QLLKRFSMIE SQMANNPDSD TYVKLASEYS ELQDVVGKIR
60 70 80 90 100
ELSDARMEAS DLAAMRDDAS TDAEMRALAV EELPEVEKRI AVLEQDVQIL
110 120 130 140 150
LLPKDAADDK NAILEIRAGT GGLEAALFAG DLFRMYERYA AEKGWRVELV
160 170 180 190 200
SASEGDAGGY KEIIATVSGK GVFSKLKFES GVHRVQRVPE TEAGGRIHTS
210 220 230 240 250
AATVAVLPEA EDIDIEIRNE DIRIDTMRAS GAGGQHVNTT DSAVRITHIP
260 270 280 290 300
TGIMVVQAEK SQHQNRARAM QILRARLYDM ERQKAESERS QARRSQVGSG
310 320 330 340 350
DRSERIRTYN FPQGRVTDHR INLTLYKLDR VMEGELDELV DALISDHQTA

LLAELGEQP
Length:359
Mass (Da):39,909
Last modified:April 3, 2002 - v2
Checksum:i9B447F031AD72D84
GO

Sequence cautioni

The sequence AAL51373.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL51373.1. Different initiation.
PIRiAB3276.
RefSeqiNP_539109.2. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL51373; AAL51373; BMEI0191.
GeneIDi1195903.
KEGGibme:BMEI0191.
PATRICi17850339. VBIBruMel92729_0201.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL51373.1 . Different initiation.
PIRi AB3276.
RefSeqi NP_539109.2. NC_003317.1.

3D structure databases

ProteinModelPortali Q8YJ95.
SMRi Q8YJ95. Positions 68-355.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI0191.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL51373 ; AAL51373 ; BMEI0191 .
GeneIDi 1195903.
KEGGi bme:BMEI0191.
PATRICi 17850339. VBIBruMel92729_0201.

Phylogenomic databases

HOGENOMi HOG000074815.
KOi K02835.
OMAi NDINDRE.
OrthoDBi EOG6TN48J.

Family and domain databases

Gene3Di 3.30.160.20. 1 hit.
HAMAPi MF_00093. Rel_fac_1.
InterProi IPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view ]
Pfami PF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view ]
SMARTi SM00937. PCRF. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00019. prfA. 1 hit.
PROSITEi PS00745. RF_PROK_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiRF1_BRUME
AccessioniPrimary (citable) accession number: Q8YJ95
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2002
Last sequence update: April 3, 2002
Last modified: October 29, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3