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Q8YJ80

- OBG_BRUME

UniProt

Q8YJ80 - OBG_BRUME

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Protein

GTPase Obg

Gene

obg

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.UniRule annotation

Cofactori

Mg2+UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi166 – 1738GTPUniRule annotation
Nucleotide bindingi212 – 2165GTPUniRule annotation
Nucleotide bindingi279 – 2824GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase ObgUniRule annotation
Alternative name(s):
GTP-binding protein ObgUniRule annotation
Gene namesi
Name:obgUniRule annotation
Ordered Locus Names:BMEI0206
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 341341GTPase ObgPRO_0000385769Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BMEI0206.

Structurei

3D structure databases

ProteinModelPortaliQ8YJ80.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini160 – 327168OBG-type GAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000019084.
KOiK03979.
OrthoDBiEOG6H1Q1M.

Family and domain databases

Gene3Di2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_01454. GTPase_Obg.
InterProiIPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamiPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFiPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsiTIGR02729. Obg_CgtA. 1 hit.
PROSITEiPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YJ80-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKFLDQAKIY IRSGNGGAGA VSFRREKFLE FGGPDGGDGG RGGDVWVEAV
60 70 80 90 100
DGLNTLIDYR YQQHFKAKTG MHGMGRNMTG GKGDDVVLRV PVGTQIFEED
110 120 130 140 150
NETLICDITE VGQRYRLAKG GNGGFGNLHF TTSTNRAPRR ANPGQEGIER
160 170 180 190 200
TIWLRLKLIA DAGLVGLPNA GKSTFLASVT AAKPKIADYP FTTLHPNLGV
210 220 230 240 250
ARIDGREFVI ADIPGLIEGA SEGVGLGDRF LGHVERTRVL LHLVSAQEED
260 270 280 290 300
VAKAYQVIRG ELEAYEHGLA DKPEIVALSQ VDTLDPETRK AKVKALKKAC
310 320 330 340
GCEPLLLSAV SHEGLNDTLR QLARIIDLSR AEEAGTAQAE E
Length:341
Mass (Da):36,789
Last modified:October 13, 2009 - v2
Checksum:i7C440746D70AB29B
GO

Sequence cautioni

The sequence AAL51388.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51388.1. Different initiation.
PIRiAI3277.
RefSeqiNP_539124.2. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL51388; AAL51388; BMEI0206.
GeneIDi1195918.
KEGGibme:BMEI0206.
PATRICi17850398. VBIBruMel92729_0222.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51388.1 . Different initiation.
PIRi AI3277.
RefSeqi NP_539124.2. NC_003317.1.

3D structure databases

ProteinModelPortali Q8YJ80.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI0206.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL51388 ; AAL51388 ; BMEI0206 .
GeneIDi 1195918.
KEGGi bme:BMEI0206.
PATRICi 17850398. VBIBruMel92729_0222.

Phylogenomic databases

HOGENOMi HOG000019084.
KOi K03979.
OrthoDBi EOG6H1Q1M.

Family and domain databases

Gene3Di 2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_01454. GTPase_Obg.
InterProi IPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view ]
PANTHERi PTHR11702:SF3. PTHR11702:SF3. 1 hit.
Pfami PF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view ]
PIRSFi PIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSi PR00326. GTP1OBG.
SUPFAMi SSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsi TIGR02729. Obg_CgtA. 1 hit.
PROSITEi PS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiOBG_BRUME
AccessioniPrimary (citable) accession number: Q8YJ80
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: October 13, 2009
Last modified: November 26, 2014
This is version 81 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3