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Q8YJ80 (OBG_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
GTPase Obg
Alternative name(s):
GTP-binding protein Obg
Gene names
Name:obg
Ordered Locus Names:BMEI0206
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate By similarity. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control Potential. HAMAP-Rule MF_01454

Cofactor

Magnesium Potential.

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01454

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01454.

Sequence similarities

Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

Contains 1 OBG-type G (guanine nucleotide-binding) domain.

Sequence caution

The sequence AAL51388.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 341341GTPase Obg HAMAP-Rule MF_01454
PRO_0000385769

Regions

Domain160 – 327168OBG-type G
Nucleotide binding166 – 1738GTP By similarity
Nucleotide binding212 – 2165GTP By similarity
Nucleotide binding279 – 2824GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YJ80 [UniParc].

Last modified October 13, 2009. Version 2.
Checksum: 7C440746D70AB29B

FASTA34136,789
        10         20         30         40         50         60 
MKFLDQAKIY IRSGNGGAGA VSFRREKFLE FGGPDGGDGG RGGDVWVEAV DGLNTLIDYR 

        70         80         90        100        110        120 
YQQHFKAKTG MHGMGRNMTG GKGDDVVLRV PVGTQIFEED NETLICDITE VGQRYRLAKG 

       130        140        150        160        170        180 
GNGGFGNLHF TTSTNRAPRR ANPGQEGIER TIWLRLKLIA DAGLVGLPNA GKSTFLASVT 

       190        200        210        220        230        240 
AAKPKIADYP FTTLHPNLGV ARIDGREFVI ADIPGLIEGA SEGVGLGDRF LGHVERTRVL 

       250        260        270        280        290        300 
LHLVSAQEED VAKAYQVIRG ELEAYEHGLA DKPEIVALSQ VDTLDPETRK AKVKALKKAC 

       310        320        330        340 
GCEPLLLSAV SHEGLNDTLR QLARIIDLSR AEEAGTAQAE E 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL51388.1. Different initiation.
PIRAI3277.
RefSeqNP_539124.2. NC_003317.1.

3D structure databases

ProteinModelPortalQ8YJ80.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI0206.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL51388; AAL51388; BMEI0206.
GeneID1195918.
KEGGbme:BMEI0206.
PATRIC17850398. VBIBruMel92729_0222.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000019084.
KOK03979.
OrthoDBEOG6H1Q1M.

Family and domain databases

Gene3D2.70.210.12. 1 hit.
3.40.50.300. 1 hit.
HAMAPMF_01454. GTPase_Obg.
InterProIPR014100. GTP-bd_Obg/CgtA.
IPR006074. GTP1-OBG_CS.
IPR006169. GTP1_OBG_dom.
IPR006073. GTP_binding_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR11702:SF3. PTHR11702:SF3. 1 hit.
PfamPF01018. GTP1_OBG. 1 hit.
PF01926. MMR_HSR1. 1 hit.
[Graphical view]
PIRSFPIRSF002401. GTP_bd_Obg/CgtA. 1 hit.
PRINTSPR00326. GTP1OBG.
SUPFAMSSF52540. SSF52540. 1 hit.
SSF82051. SSF82051. 1 hit.
TIGRFAMsTIGR02729. Obg_CgtA. 1 hit.
PROSITEPS51710. G_OBG. 1 hit.
PS00905. GTP1_OBG. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOBG_BRUME
AccessionPrimary (citable) accession number: Q8YJ80
Entry history
Integrated into UniProtKB/Swiss-Prot: October 13, 2009
Last sequence update: October 13, 2009
Last modified: May 14, 2014
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names