Q8YJ80 (OBG_BRUME) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 60.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: GTPase obg Alternative name(s): GTP-binding protein obg | ||||
| Gene names |
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| Organism | Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 224914 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella |
Protein attributes
| Sequence length | 341 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate By similarity. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control Potential. HAMAP MF_01454 |
| Cofactor | Magnesium Potential. |
| Subunit structure | Monomer By similarity. HAMAP MF_01454 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_01454. |
| Sequence similarities | Belongs to the GTP1/OBG family. Contains 1 G (guanine nucleotide-binding) domain. |
| Sequence caution | The sequence AAL51388.1 differs from that shown. Reason: Erroneous initiation. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | GTP-binding Nucleotide-binding |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activityInferred from electronic annotation. Source: InterPro magnesium ion bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 341 | 341 | GTPase obg HAMAP MF_01454 | PRO_0000385769 | |||||
Regions | |||||||||
| Domain | 171 – 278 | 108 | G | ||||||
| Nucleotide binding | 166 – 173 | 8 | GTP By similarity | ||||||
| Nucleotide binding | 212 – 216 | 5 | GTP By similarity | ||||||
| Nucleotide binding | 279 – 282 | 4 | GTP By similarity | ||||||
Sequences
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References
| [1] | "The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. Overbeek R.Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE008917 Genomic DNA. Translation: AAL51388.1. Different initiation. |
| PIR | AI3277. |
| RefSeq | NP_539124.2. NC_003317.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1LNZ based on UniProtKB P20964. |
| ProteinModelPortal | Q8YJ80. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1195918. |
| GenomeReviews | Gene locus BMEI0206 in contig AE008917_GR. |
| KEGG | bme:BMEI0206. |
| PATRIC | 17850398. VBIBruMel92729_0222. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG716038. |
| ProtClustDB | PRK12299. |
Enzyme and pathway databases | |
| BioCyc | BMEL224914:BMEI0206-MONOMER. |
Family and domain databases | |
| HAMAP | MF_01454. GTPase_Obg. [Tree] |
| InterPro | IPR014100. GTP-bd_Obg/CgtA. IPR006074. GTP1-OBG_CS. IPR006169. GTP1_OBG_dom. IPR006073. GTP_binding_domain. [Graphical view] |
| Gene3D | G3DSA:2.70.210.12. GTP1_OBG_sub. 1 hit. |
| KO | K03979. |
| PANTHER | PTHR11702:SF3. GTP_bd_Obg/CgtA. 1 hit. |
| Pfam | PF01018. GTP1_OBG. 1 hit. PF01926. MMR_HSR1. 1 hit. [Graphical view] |
| PIRSF | PIRSF002401. GTP_bd_Obg/CgtA. 1 hit. |
| PRINTS | PR00326. GTP1OBG. |
| SUPFAM | SSF82051. GTP1_OBG_sub. 1 hit. |
| TIGRFAMs | TIGR02729. Obg_CgtA. 1 hit. |
| PROSITE | PS00905. GTP1_OBG. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | OBG_BRUME | ||||||||
| Accession | Primary (citable) accession number: Q8YJ80 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Brucella melitensis Brucella melitensis (strain 16M): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

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