Reviewed, UniProtKB/Swiss-Prot Q8YJ42 (TAL_BRUME)

Names and origin

Protein names

Recommended name:
    Probable transaldolase
    EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	BMEI0244

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	217 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity.
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	transaldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 217	217	Probable transaldolase HAMAP MF_00494		PRO_0000173660
Sites
	Active site	83	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8YJ42-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 69E2119EDE74CA52	FASTA	217	23,407
	10 20 30 40 50 60 MKFFVDTADV KEIRELNDLG LVDGVTTNPS LILKSGRDII EVTKEICNIV KGPVSAEVAA 70 80 90 100 110 120 TEYEQMMKEA AVIARIADNI CIKLPVTLDG LKACKALTSE GHKVNMTLCF SANQALLAAK 130 140 150 160 170 180 AGATFISPFI GRLDDTGING MELIAEIRTI YDNYDFRTEI LAASVRTVNH VKEAALIGAD 190 200 210 VVTAPPATLK ALVKHPLTYK GLETFLADWA KTGQKIA

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008917 Genomic DNA. Translation: AAL51426.1.
PIR	AG3282.
RefSeq	NP_539162.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1195956.
GenomeReviews	Gene locus BMEI0244 in contig AE008917_GR.
KEGG	bme:BMEI0244.
NMPDR	fig|224914.1.peg.244.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG533000.
OMA	IHKNIVI.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0244-MON.
BRENDA	2.2.1.2. 277959.
Family and domain databases
HAMAP	MF_00494. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR018225. Transaldolase_AS. IPR004731. Transaldolase_C. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_BRUME

Accession

Primary (citable) accession number: Q8YJ42

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 7, 2003
Last sequence update:	March 1, 2002
Last modified:	December 15, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)