Q8YJ36 (ATPG_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase gamma chain

Alternative name(s):
ATP synthase F1 sector gamma subunit
F-ATPase gamma subunit

Gene names

Name:	atpG
Ordered Locus Names:	BMEI0250

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	292 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF0 complex. HAMAP MF_00815
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00815.
Sequence similarities	Belongs to the ATPase gamma chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell inner membrane Cell membrane Membrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 292	292	ATP synthase gamma chain HAMAP MF_00815		PRO_0000073250

Sequences

	Sequence		Length	Mass (Da)
	Q8YJ36 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 32EE2B53797B9BA4	FASTA	292	31,802
	10 20 30 40 50 60 MPSLKDLRNR IASVKATQKI TKAMQMVAAA KLRRAQEAAE AARPYSQRMG AVLANIAQNV 70 80 90 100 110 120 SGEDAPALMV GTGKDDVHLL VVCTAKRGLC GGFNSQIARL ARDHARKLLA EGKTVKIITV 130 140 150 160 170 180 GKKGADILRR EFSALLHDHV DLREVKQLAF VHADQIGHKI IKLFEEGAFD VCTLFYSEFK 190 200 210 220 230 240 SVISQVSTAQ QLIPASADNE AEMETAGDAI YEYEPDPAAI LSTLIPRNIS VQIFRALLEN 250 260 270 280 290 VAGEMGAKMS AMDNATRNAG DMINKLSITY NRQRQAQITK ELIEIISGAE AL

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL51432.1.
PIR	AE3283.
RefSeq	NP_539168.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YJ36.
SMR	Q8YJ36. Positions 233-292.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1195962.
GenomeReviews	Gene locus BMEI0250 in contig AE008917_GR.
KEGG	bme:BMEI0250.
PATRIC	17802120. VBIBruMel146950_3377.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG586593.
OMA	AGNLIND.
PhylomeDB	Q8YJ36.
ProtClustDB	PRK05621.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0250-MONOMER.
Family and domain databases
HAMAP	MF_00815. ATP_synth_gamma_bact. [Tree]
InterPro	IPR000131. ATPase_F1-cplx_gsu. IPR023632. ATPase_F1_gsu_CS. IPR023633. ATPase_F1_gsu_dom. [Graphical view]
KO	K02115.
PANTHER	PTHR11693. ATPase_F1_gamma. 1 hit.
Pfam	PF00231. ATP-synt. 1 hit. [Graphical view]
PRINTS	PR00126. ATPASEGAMMA.
SUPFAM	SSF52943. ATPase_gamma. 1 hit.
TIGRFAMs	TIGR01146. ATPsyn_F1gamma. 1 hit.
PROSITE	PS00153. ATPASE_GAMMA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPG_BRUME

Accession

Primary (citable) accession number: Q8YJ36

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 22, 2005
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program