Q8YJ22 (LIVB2_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Leu/Ile/Val-binding protein homolog 2

Gene names

Ordered Locus Names:

BMEI0264

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Component of an amino-acid transport system Potential.
Sequence similarities	Belongs to the leucine-binding protein family.
Sequence caution	The sequence AAL51446.1 differs from that shown. Reason: Erroneous termination at position 153. Translated as Tyr.

Ontologies

Keywords
Biological process	Amino-acid transport Transport
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	amino acid transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 23	23	Potential
	Chain	24 – 371	348	Leu/Ile/Val-binding protein homolog 2		PRO_0000285733

Sequences

	Sequence		Length	Mass (Da)
	Q8YJ22 [UniParc]. Last modified May 1, 2007. Version 2. Checksum: 803FF737C9112F5A	FASTA	371	39,507
	10 20 30 40 50 60 MKKSLFCGVC LCALVAMGGT SFADIMVGVG APLTGSQAAF GEQIKRGVEA AVAEANAKGG 70 80 90 100 110 120 MNGEQITLVY GDDAADSKQG ISVANKFVGD GVKFVIGHFN SGVSIPTSDI YAENGVLMIA 130 140 150 160 170 180 PGTTNPTFTE RELWNTFRTC RRDDKQGIVA GKYMADNYKD GKVAILHDKT PYGQGLADET 190 200 210 220 230 240 KKSLNENGMK ETLYEGVNQG DKDFSALISK MKAAGITAVY WGGMHPEAGL LIRQMADQGL 250 260 270 280 290 300 KAQFISGDGI VSNELASIAG DAVAGVMNTF GPDPRDDKAN AELIKAFRDK GFEPEAYTFY 310 320 330 340 350 360 AYAGVQSLVN AANAAGSNDP MEVATAMKEK GPFKTVLGDI SFDAKGDPSL SPYVMFEWRK 370 GEDGKYNYFQ K

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL51446.1. Sequence problems.
PIR	AC3285.
RefSeq	NP_539182.1. NC_003317.1.
3D structure databases
HSSP	HSSP built from PDB template 1Z16 based on UniProtKB P0AD96.
ProteinModelPortal	Q8YJ22.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1195976.
GenomeReviews	Gene locus BMEI0264 in contig AE008917_GR.
KEGG	bme:BMEI0264.
PATRIC	17850533. VBIBruMel92729_0289.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG695960.
PhylomeDB	Q8YJ22.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0264-MONOMER.
Family and domain databases
InterPro	IPR001828. ANF_lig-bd_rcpt. IPR000709. Leu_Ile_Val-bd. [Graphical view]
KO	K01999.
Pfam	PF01094. ANF_receptor. 1 hit. [Graphical view]
PRINTS	PR00337. LEUILEVALBP.
ProtoNet	Search...

Entry information

Entry name

LIVB2_BRUME

Accession

Primary (citable) accession number: Q8YJ22

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	January 25, 2012
This is version 53 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program