Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8YJ03

- THIP_BRUME

UniProt

Q8YJ03 - THIP_BRUME

Protein

Thiamine transport system permease protein ThiP

Gene

thiP

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 2 (03 Apr 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane By similarity.By similarity

    GO - Molecular functioni

    1. transporter activity Source: InterPro

    GO - Biological processi

    1. thiamine transport Source: InterPro

    Keywords - Biological processi

    Transport

    Enzyme and pathway databases

    BioCyciBMEL224914:GCJ0-294-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thiamine transport system permease protein ThiP
    Gene namesi
    Name:thiP
    Ordered Locus Names:BMEI0284
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome I

    Subcellular locationi

    Cell inner membrane By similarity; Multi-pass membrane protein PROSITE-ProRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 543543Thiamine transport system permease protein ThiPPRO_0000282909Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).Curated

    Protein-protein interaction databases

    STRINGi224914.BMEI0284.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YJ03.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei19 – 3921HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei64 – 8421HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei102 – 12221HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei142 – 16221HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei205 – 22521HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei250 – 27021HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei300 – 32021HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei343 – 36321HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei379 – 39921HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei406 – 42621HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei468 – 48821HelicalPROSITE-ProRule annotationAdd
    BLAST
    Transmembranei510 – 53021HelicalPROSITE-ProRule annotationAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini62 – 266205ABC transmembrane type-1 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini339 – 530192ABC transmembrane type-1 2PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000272487.
    KOiK02063.
    OMAiSYRTNDA.
    OrthoDBiEOG6JDW8K.

    Family and domain databases

    Gene3Di1.10.3720.10. 2 hits.
    InterProiIPR000515. MetI-like.
    IPR005947. ThiP_ABC_transpt.
    [Graphical view]
    PfamiPF00528. BPD_transp_1. 2 hits.
    [Graphical view]
    SUPFAMiSSF161098. SSF161098. 2 hits.
    TIGRFAMsiTIGR01253. thiP. 1 hit.
    PROSITEiPS50928. ABC_TM1. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8YJ03-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTATPARRTS LASPATKPVA GGLALAFLAT LAGGALLALA LEAGGGGFDA    50
    AANFDTYLWR VARFTIWQAV ASSLLSVLFA IPIARALYAE ARFPGRGLIL 100
    RLFAQPLALP ALVAVLGVTS IYGRNGLIAH ISDMLGHPMQ PDIYGIAGIL 150
    IAHIFFNMPL AVRLLLAAYE SIPDDHWKLA AQLGMGSRAR FRLIDWPVIR 200
    RSLPGMIGLV FMLCVTSFTT VLTLGGGPRA TTLEVAIYQS LHFDFDPARA 250
    VALTFTQLAL TLLILLILRL TGRPSEEGFT QTATPRRYGS PRKTERLFNI 300
    IVIALGFLYV ALPIAGVVVS GLTADLVRLL SERIVWHAIA TSLALGFSAA 350
    LLAVFLSLAL VAAREATRNA RIANIFDTGA SLILVMPPIV IGAGWFILLR 400
    HFTDPFVMAP LMVVTVNAAM AMPFAVRLLR PAWDTAASRH NKLCSQLGIK 450
    GFNRLRLIDW PSIRRPCGMA FAFAMALSLG DLGTIALFGS DALVTLPYLL 500
    LQRMGSYRTF DAAGLALILG VLCLALMMIA DRAAASRKEA FLQ 543
    Length:543
    Mass (Da):58,303
    Last modified:April 3, 2007 - v2
    Checksum:i5FADDDB7893B96AA
    GO

    Sequence cautioni

    The sequence AAL51465.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL51465.1. Different initiation.
    PIRiAF3287.
    RefSeqiNP_539201.1. NC_003317.1.

    Genome annotation databases

    EnsemblBacteriaiAAL51465; AAL51465; BMEI0284.
    GeneIDi1195995.
    KEGGibme:BMEI0284.
    PATRICi17850580. VBIBruMel92729_0312.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL51465.1 . Different initiation.
    PIRi AF3287.
    RefSeqi NP_539201.1. NC_003317.1.

    3D structure databases

    ProteinModelPortali Q8YJ03.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEI0284.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL51465 ; AAL51465 ; BMEI0284 .
    GeneIDi 1195995.
    KEGGi bme:BMEI0284.
    PATRICi 17850580. VBIBruMel92729_0312.

    Phylogenomic databases

    HOGENOMi HOG000272487.
    KOi K02063.
    OMAi SYRTNDA.
    OrthoDBi EOG6JDW8K.

    Enzyme and pathway databases

    BioCyci BMEL224914:GCJ0-294-MONOMER.

    Family and domain databases

    Gene3Di 1.10.3720.10. 2 hits.
    InterProi IPR000515. MetI-like.
    IPR005947. ThiP_ABC_transpt.
    [Graphical view ]
    Pfami PF00528. BPD_transp_1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF161098. SSF161098. 2 hits.
    TIGRFAMsi TIGR01253. thiP. 1 hit.
    PROSITEi PS50928. ABC_TM1. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiTHIP_BRUME
    AccessioniPrimary (citable) accession number: Q8YJ03
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 3, 2007
    Last sequence update: April 3, 2007
    Last modified: October 1, 2014
    This is version 82 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3