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Protein

Elongation factor P

Gene

efp

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.UniRule annotation

Pathwayi: polypeptide chain elongation

This protein is involved in the pathway polypeptide chain elongation, which is part of Protein biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway polypeptide chain elongation and in Protein biosynthesis.

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00345.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor PUniRule annotation
Short name:
EF-PUniRule annotation
Gene namesi
Name:efpUniRule annotation
Ordered Locus Names:BMEI0327
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000942131 – 186Elongation factor PAdd BLAST186

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_3002.

Structurei

3D structure databases

ProteinModelPortaliQ8YIW2.
SMRiQ8YIW2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the elongation factor P family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DRH. Bacteria.
COG0231. LUCA.
HOGENOMiHOG000010048.
KOiK02356.
OMAiNTFSAGH.

Family and domain databases

CDDicd04470. S1_EF-P_repeat_1. 1 hit.
cd05794. S1_EF-P_repeat_2. 1 hit.
Gene3Di2.30.30.30. 1 hit.
HAMAPiMF_00141. EF_P. 1 hit.
InterProiView protein in InterPro
IPR015365. Elong-fact-P_C.
IPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR020599. Transl_elong_fac_P/YeiP.
IPR013185. Transl_elong_KOW-like.
IPR001059. Transl_elong_P/YeiP_cen.
IPR013852. Transl_elong_P/YeiP_CS.
IPR011768. Transl_elongation_fac_P.
IPR008991. Translation_prot_SH3-like_sf.
PfamiView protein in Pfam
PF01132. EFP. 1 hit.
PF08207. EFP_N. 1 hit.
PF09285. Elong-fact-P_C. 1 hit.
PIRSFiPIRSF005901. EF-P. 1 hit.
SMARTiView protein in SMART
SM01185. EFP. 1 hit.
SM00841. Elong-fact-P_C. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 2 hits.
TIGRFAMsiTIGR00038. efp. 1 hit.
PROSITEiView protein in PROSITE
PS01275. EFP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YIW2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKINGNEIRP GNVIEHEGGL WVAVKTNAVK PGKGGAYNQV ELKNLINGTK
60 70 80 90 100
LNERFRAAES VERVRLEQKD FSFLYEQGEA LIFMDTETYE QLELQKDFVG
110 120 130 140 150
DRAAFLQDGM MVTVELYEEK PIGIRLPDQV TLAITEADPV VKGQTAASSY
160 170 180
KPAVLENGIR IPVPPFIASG ERVIVDTNEL TYISRA
Length:186
Mass (Da):20,700
Last modified:March 1, 2002 - v1
Checksum:i0DB78F78885EC53A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51508.1.
PIRiAI3292.
RefSeqiWP_002964799.1. NZ_GG703781.1.

Genome annotation databases

EnsemblBacteriaiAAL51508; AAL51508; BMEI0327.
GeneIDi29593079.
KEGGibme:BMEI0327.
bmel:DK63_1107.
PATRICifig|224914.52.peg.1166.

Similar proteinsi

Entry informationi

Entry nameiEFP_BRUME
AccessioniPrimary (citable) accession number: Q8YIW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: March 1, 2002
Last modified: November 22, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families