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Protein

Putative fluoride ion transporter CrcB 1

Gene

crcB1

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Putative fluoride ion transporter CrcB 1
Gene namesi
Name:crcB1
Ordered Locus Names:BMEI0633
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

  • Cell inner membrane ; Multi-pass membrane protein

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalAdd BLAST21
Transmembranei59 – 79HelicalAdd BLAST21
Transmembranei98 – 118HelicalAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001100711 – 123Putative fluoride ion transporter CrcB 1Add BLAST123

Interactioni

Protein-protein interaction databases

STRINGi224914.BAWG_2609.

Structurei

3D structure databases

SMRiQ8YI12.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CrcB (TC 9.B.71) family. [View classification]

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41085Q9. Bacteria.
COG0239. LUCA.
HOGENOMiHOG000052573.
KOiK06199.
OMAiTWMLETH.

Family and domain databases

HAMAPiMF_00454. CrcB. 1 hit.
InterProiView protein in InterPro
IPR003691. CrcB.
PANTHERiPTHR28259. PTHR28259. 1 hit.
PfamiView protein in Pfam
PF02537. CRCB. 1 hit.
TIGRFAMsiTIGR00494. crcB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YI12-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWVGLGGGVG SLGRWWIGRI VGEYHHGAFP LGTFLINISG AFVIGYLSVL
60 70 80 90 100
FGVDWHDRYG TMLNAGVLTG ILGGYTTFSS MQLDAVKLSH KGQGGLAVFY
110 120
LVASVLSGLF AAWLGAMLAH LQG
Length:123
Mass (Da):13,003
Last modified:March 1, 2002 - v1
Checksum:i659643B33775A7BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51814.1.
PIRiAC3331.

Genome annotation databases

EnsemblBacteriaiAAL51814; AAL51814; BMEI0633.
KEGGibme:BMEI0633.

Similar proteinsi

Entry informationi

Entry nameiCRCB1_BRUME
AccessioniPrimary (citable) accession number: Q8YI12
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: March 1, 2002
Last modified: June 7, 2017
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families