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Protein

Urease accessory protein UreF 1

Gene

ureF1

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processNickel insertion

Names & Taxonomyi

Protein namesi
Recommended name:
Urease accessory protein UreF 1
Gene namesi
Name:ureF1
Ordered Locus Names:BMEI0645
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003440901 – 241Urease accessory protein UreF 1Add BLAST241

Interactioni

Subunit structurei

UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

Protein-protein interaction databases

STRINGi224914.BAWG_2620.

Structurei

3D structure databases

SMRiQ8YI00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UreF family.

Phylogenomic databases

eggNOGiENOG4108S0R. Bacteria.
COG0830. LUCA.
HOGENOMiHOG000049665.
KOiK03188.
OMAiGEEQQLM.

Family and domain databases

HAMAPiMF_01385. UreF. 1 hit.
InterProiView protein in InterPro
IPR002639. UreF.
PfamiView protein in Pfam
PF01730. UreF. 1 hit.
PIRSFiPIRSF009467. Ureas_acces_UreF. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YI00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRTATITEFS SSYRSLPGLL HLLQFGDSAL PIGGFSFSNG LESAIQQNLV
60 70 80 90 100
HDKETLREFT LTAMNQAATS DRIALLTAHR AARADDRGAL QVIDKAVFER
110 120 130 140 150
KLNEETRLMT VRMGRKLCEL SASIIDDRLN RDWLECIKTA ETPGTHPVSL
160 170 180 190 200
GLAFAALDVD GRDAFGAQQY GVATTILGAA LRLMRVSFMD TQKILLEATS
210 220 230 240
TVAPAYEEIA DAGIEDMASF APMVDILAAV HVKGHVRMFM N
Length:241
Mass (Da):26,332
Last modified:March 1, 2002 - v1
Checksum:i6E1AD9DDC33F7F6C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51826.1.
PIRiAG3332.

Genome annotation databases

EnsemblBacteriaiAAL51826; AAL51826; BMEI0645.
KEGGibme:BMEI0645.

Similar proteinsi

Entry informationi

Entry nameiUREF1_BRUME
AccessioniPrimary (citable) accession number: Q8YI00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: March 1, 2002
Last modified: June 7, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families