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Protein

50S ribosomal protein L3

Gene

rplC

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L3UniRule annotation
Gene namesi
Name:rplCUniRule annotation
Ordered Locus Names:BMEI0757
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 23723750S ribosomal protein L3PRO_0000077075Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei151 – 1511N5-methylglutamineUniRule annotation

Post-translational modificationi

Methylated by PrmB.UniRule annotation

Keywords - PTMi

Methylation

Proteomic databases

PRIDEiQ8YHP0.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BAWG_2729.

Structurei

3D structure databases

ProteinModelPortaliQ8YHP0.
SMRiQ8YHP0. Positions 4-209.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L3P family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000100368.
KOiK02906.
OMAiKRMAGRY.
OrthoDBiEOG6WDSMH.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YHP0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSGVIAQKL GMTRVYNDAG EHVPVTVLRM ENCHVVAQRT VEKNGYTAVQ
60 70 80 90 100
LGVGMAKVKN TSKAMRGHFA KAEVEPKAKL AEFRVSPDNL LEVGVEITAE
110 120 130 140 150
HFVAGQKVDV TGTSIGKGFA GVMKRHNFGG HRASHGNSIT HRSHGSTGQR
160 170 180 190 200
QDPGKVFKGK KMAGHMGQTR VTTQNIEVVS TDSDRGLILV RGAVPGSKGA
210 220 230
WILVRDAVKA SLPENAPKPA GLRAGAKAEA AATEGGE
Length:237
Mass (Da):25,064
Last modified:February 16, 2004 - v2
Checksum:iC89617EBC6E50AE5
GO

Sequence cautioni

The sequence AAL51938.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51938.1. Different initiation.
PIRiAG3346.
RefSeqiNP_539674.2. NC_003317.1.
WP_002964362.1. NZ_GG703780.1.

Genome annotation databases

EnsemblBacteriaiAAL51938; AAL51938; BMEI0757.
GeneIDi3787853.
KEGGibme:BMEI0757.
PATRICi17851701. VBIBruMel92729_0854.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51938.1. Different initiation.
PIRiAG3346.
RefSeqiNP_539674.2. NC_003317.1.
WP_002964362.1. NZ_GG703780.1.

3D structure databases

ProteinModelPortaliQ8YHP0.
SMRiQ8YHP0. Positions 4-209.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224914.BAWG_2729.

Proteomic databases

PRIDEiQ8YHP0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL51938; AAL51938; BMEI0757.
GeneIDi3787853.
KEGGibme:BMEI0757.
PATRICi17851701. VBIBruMel92729_0854.

Phylogenomic databases

HOGENOMiHOG000100368.
KOiK02906.
OMAiKRMAGRY.
OrthoDBiEOG6WDSMH.

Family and domain databases

HAMAPiMF_01325_B. Ribosomal_L3_B.
InterProiIPR000597. Ribosomal_L3.
IPR019927. Ribosomal_L3_bac/org-type.
IPR019926. Ribosomal_L3_CS.
IPR009000. Transl_B-barrel.
[Graphical view]
PANTHERiPTHR11229. PTHR11229. 1 hit.
PfamiPF00297. Ribosomal_L3. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 1 hit.
TIGRFAMsiTIGR03625. L3_bact. 1 hit.
PROSITEiPS00474. RIBOSOMAL_L3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiRL3_BRUME
AccessioniPrimary (citable) accession number: Q8YHP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: February 16, 2004
Last modified: June 24, 2015
This is version 71 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.