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Q8YHN9

- RL4_BRUME

UniProt

Q8YHN9 - RL4_BRUME

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Protein

50S ribosomal protein L4

Gene

rplD

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).By similarity
Forms part of the polypeptide exit tunnel.By similarity

GO - Molecular functioni

  1. rRNA binding Source: UniProtKB-HAMAP
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L4
Gene namesi
Name:rplD
Ordered Locus Names:BMEI0758
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20620650S ribosomal protein L4PRO_0000129193Add
BLAST

Proteomic databases

PRIDEiQ8YHN9.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.By similarity

Protein-protein interaction databases

STRINGi224914.BMEI0758.

Structurei

3D structure databases

ProteinModelPortaliQ8YHN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L4P family.Curated

Phylogenomic databases

HOGENOMiHOG000248767.
KOiK02926.
OrthoDBiEOG6M0T9G.

Family and domain databases

Gene3Di3.40.1370.10. 1 hit.
HAMAPiMF_01328_B. Ribosomal_L4_B.
InterProiIPR002136. Ribosomal_L4/L1e.
IPR013005. Ribosomal_L4/L1e_bac-type.
IPR023574. Ribosomal_L4_dom.
[Graphical view]
PANTHERiPTHR10746. PTHR10746. 1 hit.
PfamiPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMiSSF52166. SSF52166. 1 hit.
TIGRFAMsiTIGR03953. rplD_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YHN9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDLTITTLEG KDAGKVKLNE EIFGLDPRDD ILQRVVRWQL ARRQQGSHKA
60 70 80 90 100
QGRGDVSRTG SKMYKQKGTG RARHHSARAP QFRGGGQAHG PVVRNHDHDL
110 120 130 140 150
PKKVRALGLR HALSAKAKAS DLIIIDDLAS ADAKTKQLVS QFAKLGLENA
160 170 180 190 200
LLIGGAEIDA NFQRAASNIP NIDVLPVQGI NVYDILRRGK LVLSKAAVEA

LEERFK
Length:206
Mass (Da):22,561
Last modified:August 16, 2004 - v2
Checksum:i1CE73FA611BD2557
GO

Sequence cautioni

The sequence AAL51939.1 differs from that shown. Reason: Frameshift at position 167. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51939.1. Frameshift.
PIRiAH3346.
RefSeqiNP_539675.1. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL51939; AAL51939; BMEI0758.
GeneIDi1196469.
KEGGibme:BMEI0758.
PATRICi17851703. VBIBruMel92729_0855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51939.1 . Frameshift.
PIRi AH3346.
RefSeqi NP_539675.1. NC_003317.1.

3D structure databases

ProteinModelPortali Q8YHN9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI0758.

Proteomic databases

PRIDEi Q8YHN9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL51939 ; AAL51939 ; BMEI0758 .
GeneIDi 1196469.
KEGGi bme:BMEI0758.
PATRICi 17851703. VBIBruMel92729_0855.

Phylogenomic databases

HOGENOMi HOG000248767.
KOi K02926.
OrthoDBi EOG6M0T9G.

Enzyme and pathway databases

BioCyci BMEL224914:GCJ0-785-MONOMER.

Family and domain databases

Gene3Di 3.40.1370.10. 1 hit.
HAMAPi MF_01328_B. Ribosomal_L4_B.
InterProi IPR002136. Ribosomal_L4/L1e.
IPR013005. Ribosomal_L4/L1e_bac-type.
IPR023574. Ribosomal_L4_dom.
[Graphical view ]
PANTHERi PTHR10746. PTHR10746. 1 hit.
Pfami PF00573. Ribosomal_L4. 1 hit.
[Graphical view ]
SUPFAMi SSF52166. SSF52166. 1 hit.
TIGRFAMsi TIGR03953. rplD_bact. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiRL4_BRUME
AccessioniPrimary (citable) accession number: Q8YHN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: August 16, 2004
Last modified: October 1, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3