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Q8YHN9

- RL4_BRUME

UniProt

Q8YHN9 - RL4_BRUME

Protein

50S ribosomal protein L4

Gene

rplD

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 2 (16 Aug 2004)
      Previous versions | rss
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    Functioni

    One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome By similarity.By similarity
    Forms part of the polypeptide exit tunnel.By similarity

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-HAMAP
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Enzyme and pathway databases

    BioCyciBMEL224914:GCJ0-785-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L4
    Gene namesi
    Name:rplD
    Ordered Locus Names:BMEI0758
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome I

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 20620650S ribosomal protein L4PRO_0000129193Add
    BLAST

    Proteomic databases

    PRIDEiQ8YHN9.

    Interactioni

    Subunit structurei

    Part of the 50S ribosomal subunit.By similarity

    Protein-protein interaction databases

    STRINGi224914.BMEI0758.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YHN9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L4P family.Curated

    Phylogenomic databases

    HOGENOMiHOG000248767.
    KOiK02926.
    OrthoDBiEOG6M0T9G.

    Family and domain databases

    Gene3Di3.40.1370.10. 1 hit.
    HAMAPiMF_01328_B. Ribosomal_L4_B.
    InterProiIPR002136. Ribosomal_L4/L1e.
    IPR013005. Ribosomal_L4/L1e_bac-type.
    IPR023574. Ribosomal_L4_dom.
    [Graphical view]
    PANTHERiPTHR10746. PTHR10746. 1 hit.
    PfamiPF00573. Ribosomal_L4. 1 hit.
    [Graphical view]
    SUPFAMiSSF52166. SSF52166. 1 hit.
    TIGRFAMsiTIGR03953. rplD_bact. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8YHN9-1 [UniParc]FASTAAdd to Basket

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    MDLTITTLEG KDAGKVKLNE EIFGLDPRDD ILQRVVRWQL ARRQQGSHKA    50
    QGRGDVSRTG SKMYKQKGTG RARHHSARAP QFRGGGQAHG PVVRNHDHDL 100
    PKKVRALGLR HALSAKAKAS DLIIIDDLAS ADAKTKQLVS QFAKLGLENA 150
    LLIGGAEIDA NFQRAASNIP NIDVLPVQGI NVYDILRRGK LVLSKAAVEA 200
    LEERFK 206
    Length:206
    Mass (Da):22,561
    Last modified:August 16, 2004 - v2
    Checksum:i1CE73FA611BD2557
    GO

    Sequence cautioni

    The sequence AAL51939.1 differs from that shown. Reason: Frameshift at position 167.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL51939.1. Frameshift.
    PIRiAH3346.
    RefSeqiNP_539675.1. NC_003317.1.

    Genome annotation databases

    EnsemblBacteriaiAAL51939; AAL51939; BMEI0758.
    GeneIDi1196469.
    KEGGibme:BMEI0758.
    PATRICi17851703. VBIBruMel92729_0855.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL51939.1 . Frameshift.
    PIRi AH3346.
    RefSeqi NP_539675.1. NC_003317.1.

    3D structure databases

    ProteinModelPortali Q8YHN9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEI0758.

    Proteomic databases

    PRIDEi Q8YHN9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL51939 ; AAL51939 ; BMEI0758 .
    GeneIDi 1196469.
    KEGGi bme:BMEI0758.
    PATRICi 17851703. VBIBruMel92729_0855.

    Phylogenomic databases

    HOGENOMi HOG000248767.
    KOi K02926.
    OrthoDBi EOG6M0T9G.

    Enzyme and pathway databases

    BioCyci BMEL224914:GCJ0-785-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1370.10. 1 hit.
    HAMAPi MF_01328_B. Ribosomal_L4_B.
    InterProi IPR002136. Ribosomal_L4/L1e.
    IPR013005. Ribosomal_L4/L1e_bac-type.
    IPR023574. Ribosomal_L4_dom.
    [Graphical view ]
    PANTHERi PTHR10746. PTHR10746. 1 hit.
    Pfami PF00573. Ribosomal_L4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52166. SSF52166. 1 hit.
    TIGRFAMsi TIGR03953. rplD_bact. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiRL4_BRUME
    AccessioniPrimary (citable) accession number: Q8YHN9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: August 16, 2004
    Last modified: October 1, 2014
    This is version 64 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3