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Protein

50S ribosomal protein L4

Gene

rplD

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).By similarity
Forms part of the polypeptide exit tunnel.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding, rRNA-binding

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-785-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L4
Gene namesi
Name:rplD
Ordered Locus Names:BMEI0758
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20620650S ribosomal protein L4PRO_0000129193Add
BLAST

Proteomic databases

PRIDEiQ8YHN9.

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.By similarity

Protein-protein interaction databases

STRINGi224914.BAWG_2730.

Structurei

3D structure databases

ProteinModelPortaliQ8YHN9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L4P family.Curated

Phylogenomic databases

HOGENOMiHOG000248767.
KOiK02926.
OrthoDBiEOG6M0T9G.

Family and domain databases

Gene3Di3.40.1370.10. 1 hit.
HAMAPiMF_01328_B. Ribosomal_L4_B.
InterProiIPR002136. Ribosomal_L4/L1e.
IPR023574. Ribosomal_L4_dom.
IPR013005. Ribosomal_uL4/L1e.
[Graphical view]
PANTHERiPTHR10746. PTHR10746. 1 hit.
PfamiPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMiSSF52166. SSF52166. 1 hit.
TIGRFAMsiTIGR03953. rplD_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YHN9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLTITTLEG KDAGKVKLNE EIFGLDPRDD ILQRVVRWQL ARRQQGSHKA
60 70 80 90 100
QGRGDVSRTG SKMYKQKGTG RARHHSARAP QFRGGGQAHG PVVRNHDHDL
110 120 130 140 150
PKKVRALGLR HALSAKAKAS DLIIIDDLAS ADAKTKQLVS QFAKLGLENA
160 170 180 190 200
LLIGGAEIDA NFQRAASNIP NIDVLPVQGI NVYDILRRGK LVLSKAAVEA

LEERFK
Length:206
Mass (Da):22,561
Last modified:August 16, 2004 - v2
Checksum:i1CE73FA611BD2557
GO

Sequence cautioni

The sequence AAL51939.1 differs from that shown. Reason: Frameshift at position 167. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51939.1. Frameshift.
PIRiAH3346.
RefSeqiWP_002964361.1. NZ_GG703780.1.

Genome annotation databases

EnsemblBacteriaiAAL51939; AAL51939; BMEI0758.
GeneIDi3788913.
KEGGibme:BMEI0758.
PATRICi17851703. VBIBruMel92729_0855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51939.1. Frameshift.
PIRiAH3346.
RefSeqiWP_002964361.1. NZ_GG703780.1.

3D structure databases

ProteinModelPortaliQ8YHN9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224914.BAWG_2730.

Proteomic databases

PRIDEiQ8YHN9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL51939; AAL51939; BMEI0758.
GeneIDi3788913.
KEGGibme:BMEI0758.
PATRICi17851703. VBIBruMel92729_0855.

Phylogenomic databases

HOGENOMiHOG000248767.
KOiK02926.
OrthoDBiEOG6M0T9G.

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-785-MONOMER.

Family and domain databases

Gene3Di3.40.1370.10. 1 hit.
HAMAPiMF_01328_B. Ribosomal_L4_B.
InterProiIPR002136. Ribosomal_L4/L1e.
IPR023574. Ribosomal_L4_dom.
IPR013005. Ribosomal_uL4/L1e.
[Graphical view]
PANTHERiPTHR10746. PTHR10746. 1 hit.
PfamiPF00573. Ribosomal_L4. 1 hit.
[Graphical view]
SUPFAMiSSF52166. SSF52166. 1 hit.
TIGRFAMsiTIGR03953. rplD_bact. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiRL4_BRUME
AccessioniPrimary (citable) accession number: Q8YHN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: August 16, 2004
Last modified: July 22, 2015
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.