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Protein

50S ribosomal protein L2

Gene

rplB

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L2UniRule annotation
Gene namesi
Name:rplBUniRule annotation
Ordered Locus Names:BMEI0760
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001295371 – 27750S ribosomal protein L2Add BLAST277

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BAWG_2732.

Structurei

3D structure databases

ProteinModelPortaliQ8YHN7.
SMRiQ8YHN7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL2 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CFD. Bacteria.
COG0090. LUCA.
HOGENOMiHOG000232982.
KOiK02886.
OMAiHGYIKGV.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
4.10.950.10. 1 hit.
HAMAPiMF_01320_B. Ribosomal_L2_B. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR005880. Ribosomal_L2_bac/org-type.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like_sf.
PANTHERiPTHR13691. PTHR13691. 1 hit.
PfamiView protein in Pfam
PF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
PIRSFiPIRSF002158. Ribosomal_L2. 1 hit.
SMARTiView protein in SMART
SM01383. Ribosomal_L2. 1 hit.
SM01382. Ribosomal_L2_C. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR01171. rplB_bact. 1 hit.
PROSITEiView protein in PROSITE
PS00467. RIBOSOMAL_L2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YHN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKHFNPIT PGQRQLVIVD RSELYKGKPV KSLTEGLSKK GGRNNTGRIT
60 70 80 90 100
VRFQGGGHKR SYRFIDFKRR KLDVVGTVER LEYDPNRTAF IALIRYTDGE
110 120 130 140 150
LAYILAPQRL AVGDQVVAGN SVDVKPGNAM PLSSMPVGTI IHNVELMPGK
160 170 180 190 200
GGQIARSAGT YAQLVGRDQG MAILRLNSGE QRLVSGACFA SVGAVSNPDH
210 220 230 240 250
GNINDGKAGR SVWRGKRPHV RGVAMNPVDH PHGGGEGRTS GGRHPVTPWG
260 270
KPTKGKKTRS NKATDKFIMR SRHQRKK
Length:277
Mass (Da):30,171
Last modified:March 1, 2002 - v1
Checksum:i4F3B6E30A3FC8059
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51941.1.
PIRiAB3347.
RefSeqiWP_004683925.1. NZ_GG703780.1.

Genome annotation databases

EnsemblBacteriaiAAL51941; AAL51941; BMEI0760.
GeneIDi29593563.
KEGGibme:BMEI0760.
bmel:DK63_662.
PATRICifig|224914.52.peg.693.

Similar proteinsi

Entry informationi

Entry nameiRL2_BRUME
AccessioniPrimary (citable) accession number: Q8YHN7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: March 1, 2002
Last modified: November 22, 2017
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families