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Protein

50S ribosomal protein L22

Gene

rplV

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).UniRule annotation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L22UniRule annotation
Gene namesi
Name:rplVUniRule annotation
Ordered Locus Names:BMEI0762
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
Proteomesi
  • UP000000419 Componenti: Chromosome I

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001251281 – 12950S ribosomal protein L22Add BLAST129

Interactioni

Subunit structurei

Part of the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BAWG_2734.

Structurei

3D structure databases

ProteinModelPortaliQ8YHN5.
SMRiQ8YHN5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the universal ribosomal protein uL22 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KAP. Bacteria.
COG0091. LUCA.
HOGENOMiHOG000205046.
KOiK02890.
OMAiPQGRAHR.

Family and domain databases

CDDicd00336. Ribosomal_L22. 1 hit.
Gene3Di3.90.470.10. 1 hit.
HAMAPiMF_01331_B. Ribosomal_L22_B. 1 hit.
InterProiView protein in InterPro
IPR001063. Ribosomal_L22.
IPR036394. Ribosomal_L22/L17_sf.
IPR005727. Ribosomal_L22_bac/chlpt-type.
PANTHERiPTHR13501. PTHR13501. 1 hit.
PfamiView protein in Pfam
PF00237. Ribosomal_L22. 1 hit.
SUPFAMiSSF54843. SSF54843. 1 hit.
TIGRFAMsiTIGR01044. rplV_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YHN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKAKAPRQL KDNEAKAVAR TLRVSPQKLN LVASMIRGKK VNAALADLTF
60 70 80 90 100
SRKRIAGTVK KTLESAIANA ENNHDLDVDA LIVAEAYVGK SIVMKRFHVR
110 120
DRGRASRIEK PFSHLTIVVR EVAEKGKAA
Length:129
Mass (Da):14,143
Last modified:March 1, 2002 - v1
Checksum:i937A62872927C7CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE008917 Genomic DNA. Translation: AAL51943.1.
PIRiAD3347.
RefSeqiWP_002964357.1. NZ_GG703780.1.

Genome annotation databases

EnsemblBacteriaiAAL51943; AAL51943; BMEI0762.
GeneIDi29593575.
KEGGibme:BMEI0762.
bmel:DK63_660.
PATRICifig|224914.52.peg.691.

Similar proteinsi

Entry informationi

Entry nameiRL22_BRUME
AccessioniPrimary (citable) accession number: Q8YHN5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2004
Last sequence update: March 1, 2002
Last modified: October 25, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families