Q8YHM5 (RL6_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L6

Gene names

Name:	rplF
Ordered Locus Names:	BMEI0772

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center By similarity. HAMAP-Rule MF_01365
Subunit structure	Part of the 50S ribosomal subunit By similarity.
Sequence similarities	Belongs to the ribosomal protein L6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 177	177	50S ribosomal protein L6 HAMAP-Rule MF_01365		PRO_0000265228

Sequences

	Sequence		Length	Mass (Da)
	Q8YHM5 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: D0285EB706C20041	FASTA	177	19,180
	10 20 30 40 50 60 MSRIGKKPVP VPAGVTASVE GQTVKAKGAK GELSFVVHDE VLVKMEDGAV RVDPRDQSRE 70 80 90 100 110 120 ARSKWGMSRT MISNIFVGVK DGFEKKLEIS GVGYRAAMQG KNLQLSLGFS HEVVYDVPAG 130 140 150 160 170 ITVAVPKPTE IVVTGIDKQQ VGQVAAEIRE YRGPEPYKGK GVKYAGEKIV RKEGKKK

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL51953.1.
PIR	AF3348.
RefSeq	NP_539689.1. NC_003317.1.
3D structure databases
HSSP	HSSP built from PDB template 1C04 based on UniProtKB P02391.
ProteinModelPortal	Q8YHM5.
SMR	Q8YHM5. Positions 2-177.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI0772.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL51953; AAL51953; BMEI0772.
GeneID	1196483.
KEGG	bme:BMEI0772.
PATRIC	17801702. VBIBruMel146950_3171.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000039903.
KO	K02933.
OMA	INNMVVG.
ProtClustDB	PRK05498.
Family and domain databases
Gene3D	3.90.930.12. 2 hits.
HAMAP	MF_01365_B. Ribosomal_L6_B.
InterPro	IPR000702. Ribosomal_L6. IPR020040. Ribosomal_L6_a/b-dom. IPR019906. Ribosomal_L6_bac-type. IPR002358. Ribosomal_L6_CS. [Graphical view]
PANTHER	PTHR11655. PTHR11655. 1 hit. PTHR11655:SF6. PTHR11655:SF6. 1 hit.
Pfam	PF00347. Ribosomal_L6. 2 hits. [Graphical view]
PIRSF	PIRSF002162. Ribosomal_L6. 1 hit.
PRINTS	PR00059. RIBOSOMALL6.
SUPFAM	SSF56053. Ribosomal_L6. 2 hits.
TIGRFAMs	TIGR03654. L6_bact. 1 hit.
PROSITE	PS00525. RIBOSOMAL_L6_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RL6_BRUME

Accession

Primary (citable) accession number: Q8YHM5

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program