Q8YHM4 (RL18_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L18

Gene names

Name:	rplR
Ordered Locus Names:	BMEI0773

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	120 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance By similarity. HAMAP-Rule MF_01337
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs By similarity.
Sequence similarities	Belongs to the ribosomal protein L18P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 120	120	50S ribosomal protein L18 HAMAP-Rule MF_01337		PRO_0000131229

Sequences

	Sequence		Length	Mass (Da)
	Q8YHM4 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 665D1B7693B029E9	FASTA	120	12,669
	10 20 30 40 50 60 MASPKETLQR RAARVRRQVK AVANGRPRLS VHRSSKNIYA QIIDDVRGVT LAAASTLDGD 70 80 90 100 110 120 LKGKLKTGAD SAAAAAVGKL VAERAVKAGV KDVVFDRGAF IYHGRVKALA EAAREGGLSF

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL51954.1.
PIR	AG3348.
RefSeq	NP_539690.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YHM4.
SMR	Q8YHM4. Positions 26-120.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI0773.
Proteomic databases
PRIDE	Q8YHM4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL51954; AAL51954; BMEI0773.
GeneID	1196484.
KEGG	bme:BMEI0773.
PATRIC	17801704. VBIBruMel146950_3172.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000248742.
KO	K02881.
OMA	GNKYHGR.
ProtClustDB	PRK05593.
Family and domain databases
HAMAP	MF_01337_B. Ribosomal_L18_B.
InterPro	IPR005484. Ribosomal_L18/L5. IPR004389. Ribosomal_L18_bac-type. [Graphical view]
Pfam	PF00861. Ribosomal_L18p. 1 hit. [Graphical view]
TIGRFAMs	TIGR00060. L18_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RL18_BRUME

Accession

Primary (citable) accession number: Q8YHM4

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 16, 2005
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program