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Q8YHG6 (Q8YHG6_BRUME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Lipid-a-disaccharide synthase EMBL AAL52016.1
EC=2.4.1.182 EMBL AAL52016.1
Gene names
Ordered Locus Names:BMEI0835
ORF Names:BAWG_2809 EMBL EEW86757.1
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835

Catalytic activity

UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Sequences

Sequence LengthMass (Da)Tools
Q8YHG6 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 165F79C77921D1DE

FASTA39543,777
        10         20         30         40         50         60 
MNETSRPLKI AIVAGEESGD LLGADLIDAL RAQTDRLVDI VGVGGDHLAE RGLKSFFDPH 

        70         80         90        100        110        120 
EIALMGLGAI LKNLPGLMLR IRQTARQIVV EKPDCVLLID SPEFTHRVAK KIRASAPSIP 

       130        140        150        160        170        180 
IVKYIAPSVW AWRPQRARAM RASIDHVLTV LPFEVEVMER LNGPQATYVG HRLTSHEPIL 

       190        200        210        220        230        240 
QARASQLVLE AQRFNADKQT LLLLPGSRRT EIQMLMEPFG KAVEQLAARI EKLEVVLPTL 

       250        260        270        280        290        300 
PRIEAMVRDL SRDWTVKPLI VTGDEEKWKA FSRADAALAA SGTVSLELAL ARIPSVLSYK 

       310        320        330        340        350        360 
ADWFARKFLM PKITIWSAAL PNIIVDEPVV PEYFNEFVRP GMLARNLERI MRPGSARQAQ 

       370        380        390 
LDGFDEVASV MKTEKPSGEI GARVLLALAE GRSAF 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL52016.1.
GG703780 Genomic DNA. Translation: EEW86757.1.
PIRAE3356.
RefSeqNP_539752.1. NC_003317.1.

3D structure databases

ProteinModelPortalQ8YHG6.
ModBaseSearch...

Protein-protein interaction databases

STRINGD0B9A1.

Protein family/group databases

CAZyGT19. Glycosyltransferase Family 19.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1196546.
GenomeReviewsGene locus BMEI0835 in contig AE008917_GR.
KEGGbme:BMEI0835.
PATRIC17801846. VBIBruMel146950_3243.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG584837.
OMAPDFNLGL.
PhylomeDBQ8YHG6.
ProtClustDBPRK00025.

Family and domain databases

InterProIPR003835. Glyco_trans_19.
[Graphical view]
KOK00748.
PfamPF02684. LpxB. 1 hit.
[Graphical view]
TIGRFAMsTIGR00215. LpxB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ8YHG6_BRUME
AccessionPrimary (citable) accession number: Q8YHG6
Secondary accession number(s): D0B9A1
Entry history
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)