Unreviewed,
UniProtKB/TrEMBL Q8YHG6 (Q8YHG6_BRUME)
Last modified
June 16, 2009.
Version 40.
History...
Clusters with 100%,
90%,
50% identity |
Third-party data |
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Names and origin
| Protein names | Submitted name: Lipid-a-disaccharide synthase EMBL AAL52016.1 EC=2.4.1.182 | ||
| Gene names |
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| Organism | Brucella melitensis [Complete proteome] [HAMAP] | ||
| Taxonomic identifier | 29459 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella |
Protein attributes
| Sequence length | 395 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. Spearmint SPM003835 |
| Catalytic activity | UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. Spearmint SPM003835 |
| Pathway | Glycolipid biosynthesis; lipid (IV)A biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-D-glucosamine: step 5/6. Spearmint SPM003835 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Lipid A biosynthesis Spearmint SPM003835 Lipid synthesis |
| Molecular function | Glycosyltransferase Spearmint SPM003835 Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | lipid A biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequences
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References
| [1] | "The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. Overbeek R.Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1. |
Cross-references
Sequence databases | |
|---|---|
| AE008917 Genomic DNA. Translation: AAL52016.1. | |
| PIR | AE3356. |
| RefSeq | NP_539752.1. |
3D structure databases | |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | GT19. Glycosyltransferase Family 19. |
Genome annotation databases | |
| GeneID | 1196546. |
| GenomeReviews | Gene locus BMEI0835 in contig AE008917_GR. |
| KEGG | bme:BMEI0835. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8YHG6. |
| OMA | Q8YHG6. DFTHRVA. |
Enzyme and pathway databases | |
| BioCyc | BMEL224914:BMEI0835-MON. |
Family and domain databases | |
| InterPro | IPR003835. Glyco_trans_19. [Graphical view] |
| Pfam | PF02684. LpxB. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00215. lpxB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | Q8YHG6_BRUME | ||||||||
| Accession | Primary (citable) accession number: Q8YHG6 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with


