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Q8YHG5

- Q8YHG5_BRUME

UniProt

Q8YHG5 - Q8YHG5_BRUME

Protein

Citrate synthase

Gene

BMEI0836

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei313 – 3131UniRule annotation
    Active sitei371 – 3711UniRule annotation

    GO - Molecular functioni

    1. citrate (Si)-synthase activity Source: InterPro

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. tricarboxylic acid cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    AcyltransferaseImported, Transferase

    Keywords - Biological processi

    Tricarboxylic acid cycleUniRule annotation

    Enzyme and pathway databases

    UniPathwayiUPA00223; UER00717.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Citrate synthaseUniRule annotation
    Gene namesi
    Ordered Locus Names:BMEI0836Imported
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)Imported
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome I

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi224914.BMEI0836.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YHG5.
    SMRiQ8YHG5. Positions 12-436.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the citrate synthase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000021224.
    OMAiYSINDIV.

    Family and domain databases

    Gene3Di1.10.230.10. 1 hit.
    1.10.580.10. 1 hit.
    InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
    IPR016143. Citrate_synth-like_sm_a-sub.
    IPR002020. Citrate_synthase-like.
    IPR016141. Citrate_synthase-like_core.
    IPR019810. Citrate_synthase_AS.
    IPR024176. Citrate_synthase_bac-typ.
    IPR010953. Citrate_synthase_typ-I.
    [Graphical view]
    PANTHERiPTHR11739. PTHR11739. 1 hit.
    PfamiPF00285. Citrate_synt. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001369. Citrate_synth. 1 hit.
    PRINTSiPR00143. CITRTSNTHASE.
    SUPFAMiSSF48256. SSF48256. 1 hit.
    TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
    PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8YHG5-1 [UniParc]FASTAAdd to Basket

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    MDMKGKTMSD KTASFTLDGK TFDLPVRKGT VGPDVVDIGP LYKNSHAFTY    50
    DPGFTSTASC ESKITYIDGD EGVLLYRGYP IDQLAEHGDF LETCYLLLYG 100
    ELPTATQKAD FDYRVTRHTM LHEQMTKFFT GFRRDAHPMA VMVGCLGAMS 150
    AFYHDSTDIT DPHQRMVASI RLIAKVPTLA AMAYKYHIGQ PFVYPKNDLD 200
    FASNFLHMCF TVPCEEYKVN PVLARAMDRI FILHADHEQN ASTSTVRLAG 250
    SSGANPFACI AAGVACLWGP AHGGANEAAL NMLSEIGSVD RIPEYIARAK 300
    DKNDPFRLMG FGHRVYKNYD PRAKIMQKTC HEVLGELGIK DDPLLDVAME 350
    LERIALTDEY FIEKKLYPNI DFYSGITLKA LGFPTEMFTV LFALARTVGW 400
    VAQWKEMIED PQQKIGRPRQ LYTGATERDY VPLAKRK 437
    Length:437
    Mass (Da):49,034
    Last modified:March 1, 2002 - v1
    Checksum:iFCCFF0970F123547
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL52017.1.
    PIRiAF3356.

    Genome annotation databases

    EnsemblBacteriaiAAL52017; AAL52017; BMEI0836.
    PATRICi17851877. VBIBruMel92729_0942.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008917 Genomic DNA. Translation: AAL52017.1 .
    PIRi AF3356.

    3D structure databases

    ProteinModelPortali Q8YHG5.
    SMRi Q8YHG5. Positions 12-436.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEI0836.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL52017 ; AAL52017 ; BMEI0836 .
    PATRICi 17851877. VBIBruMel92729_0942.

    Phylogenomic databases

    HOGENOMi HOG000021224.
    OMAi YSINDIV.

    Enzyme and pathway databases

    UniPathwayi UPA00223 ; UER00717 .

    Family and domain databases

    Gene3Di 1.10.230.10. 1 hit.
    1.10.580.10. 1 hit.
    InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
    IPR016143. Citrate_synth-like_sm_a-sub.
    IPR002020. Citrate_synthase-like.
    IPR016141. Citrate_synthase-like_core.
    IPR019810. Citrate_synthase_AS.
    IPR024176. Citrate_synthase_bac-typ.
    IPR010953. Citrate_synthase_typ-I.
    [Graphical view ]
    PANTHERi PTHR11739. PTHR11739. 1 hit.
    Pfami PF00285. Citrate_synt. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001369. Citrate_synth. 1 hit.
    PRINTSi PR00143. CITRTSNTHASE.
    SUPFAMi SSF48256. SSF48256. 1 hit.
    TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
    PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094Imported.

    Entry informationi

    Entry nameiQ8YHG5_BRUME
    AccessioniPrimary (citable) accession number: Q8YHG5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3