Q8YHF9 (MOAC_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cyclic pyranopterin monophosphate synthase accessory protein

Alternative name(s):
Molybdenum cofactor biosynthesis protein C

Gene names

Name:	moaC
Ordered Locus Names:	BMEI0842

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	165 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Together with MoaA, is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) By similarity. HAMAP-Rule MF_01224
Pathway	Cofactor biosynthesis; molybdopterin biosynthesis. HAMAP-Rule MF_01224
Sequence similarities	Belongs to the MoaC family.

Ontologies

Keywords
Biological process	Molybdenum cofactor biosynthesis
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	Mo-molybdopterin cofactor biosynthetic process Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 165	165	Cyclic pyranopterin monophosphate synthase accessory protein HAMAP-Rule MF_01224		PRO_0000097789
Sites
	Active site	129	1	Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8YHF9 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: C3C97EEAAC3D96A9	FASTA	165	17,480
	10 20 30 40 50 60 MSGKLTHIDQ TGAANMVDVG SKDETERQAV AEGAVRMKPE TLALILEGNA AKGDVIGTAR 70 80 90 100 110 120 LAGIMAAKRT SDLIPLCHPL MLTKVAVEIE PDENLPGLRV RALARLKGRT GVEMEALTAA 130 140 150 160 SVTCLTIYDM AKAVDRHMEI GSIRVIEKSG GKSGDWAVSD PASMR

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52023.1.
PIR	AD3357.
RefSeq	NP_539759.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YHF9.
SMR	Q8YHF9. Positions 12-151.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI0842.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL52023; AAL52023; BMEI0842.
GeneID	1196553.
KEGG	bme:BMEI0842.
PATRIC	17802489. VBIBruMel146950_3550.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000228417.
KO	K03637.
OMA	AEAFVEM.
ProtClustDB	PRK09364.
Enzyme and pathway databases
UniPathway	UPA00344.
Family and domain databases
Gene3D	3.30.70.640. 1 hit.
HAMAP	MF_01224_B. MoaC_B.
InterPro	IPR023045. Mo_CF_biosynth-C. IPR023046. Mo_CF_biosynth-C_bac. IPR002820. Mopterin_CF_biosynth-C_dom. [Graphical view]
PANTHER	PTHR26250. PTHR26250. 1 hit.
Pfam	PF01967. MoaC. 1 hit. [Graphical view]
SUPFAM	SSF55040. MoaC. 1 hit.
TIGRFAMs	TIGR00581. moaC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MOAC_BRUME

Accession

Primary (citable) accession number: Q8YHF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 19, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program