Reviewed, UniProtKB/Swiss-Prot Q8YH30 (RPIA_BRUME)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase A
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase A
      Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	BMEI0974

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	232 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 232	232	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158396

Sequences

	Sequence		Length	Mass (Da)
	Q8YH30-1 [UniParc]. Last modified April 23, 2003. Version 2. Checksum: 44DB818128475C1E	FASTA	232	24,336
	10 20 30 40 50 60 MDEARKLKIA AAAEALTYVK DGMRLGIGTG STAEEFVRLL AEKVKGGFRV IGVPTSERTA 70 80 90 100 110 120 KLCEELGVAL TTLEETPHLD LTIDGADEVD GELSLIKGGG GALLREKIVA AASDSMIVIA 130 140 150 160 170 180 DQSKVVETLG RFPLPIEVNR FGLGATIRAI EAAAVKCGLA GPLNLRLKDG SPFLTDGGHY 190 200 210 220 230 IVDASFGRIP DPKTLSDALF AIPGVVEHGL FIELARAAII AGTDGIRTMN RS

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008917 Genomic DNA. Translation: AAL52155.1. Different initiation.
PIR	AH3373.
RefSeq	NP_539891.1.
3D structure databases
HSSP	HSSP built from PDB template 1O8B based on UniProtKB P27252.
ModBase	Search...
Genome annotation databases
GeneID	1196685.
GenomeReviews	Gene locus BMEI0974 in contig AE008917_GR.
KEGG	bme:BMEI0974.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8YH30.
OMA	DKSIVGV.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI0974-MON.
BRENDA	5.3.1.6. 277959.
Family and domain databases
HAMAP	MF_00170. [Tree]
InterPro	IPR014036. HTH_DeoR. IPR004788. RpiA. [Graphical view]
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
ProDom	PD005813. RpiA. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_BRUME

Accession

Primary (citable) accession number: Q8YH30

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 23, 2003
Last sequence update:	April 23, 2003
Last modified:	November 3, 2009
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)