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Q8YGM0 (LOLD_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipoprotein-releasing system ATP-binding protein LolD

EC=3.6.3.-
Gene names
Name:lolD
Ordered Locus Names:BMEI1138
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE) By similarity.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family. [View classification]

Contains 1 ABC transporter domain.

Sequence caution

The sequence AAL52319.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTransport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentATP-binding cassette (ABC) transporter complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

ATPase activity

Inferred from electronic annotation. Source: InterPro

lipoprotein transporter activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 227227Lipoprotein-releasing system ATP-binding protein LolD
PRO_0000092423

Regions

Domain7 – 227221ABC transporter
Nucleotide binding43 – 508ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8YGM0 [UniParc].

Last modified May 24, 2004. Version 2.
Checksum: E49DCFD20A3462C3

FASTA22724,930
        10         20         30         40         50         60 
MAAEIILRLE RIGRAYKEAD RELIILNDAD FTLRRGEMVA LVAPSGAGKS TLLHTAGLLE 

        70         80         90        100        110        120 
RPDSGDVVLD GRSCSKLSDD ERTAVRRNDV GFVYQFHHLL PEFSALENVM LPQMIRGLSR 

       130        140        150        160        170        180 
KAAAERAQQL LEYMKIGKRA SHRPAELSGG EQQRVAIARA VANAPLVLLA DEPTGNLDPT 

       190        200        210        220 
TSSYVFGALE ALVRQSGLAA LIATHNHELA RRMDRRVTLK DGRVVDL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL52319.1. Different initiation.
PIRAD3394.
RefSeqNP_540055.1. NC_003317.1.

3D structure databases

ProteinModelPortalQ8YGM0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI1138.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL52319; AAL52319; BMEI1138.
GeneID1196849.
KEGGbme:BMEI1138.
PATRIC17852557. VBIBruMel92729_1273.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK09810.
OMAYNRGRPG.
OrthoDBEOG6T7N3V.

Enzyme and pathway databases

BioCycBMEL224914:GCJ0-1173-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR015854. ABC_transpr_LolD.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51244. LOLD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLOLD_BRUME
AccessionPrimary (citable) accession number: Q8YGM0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: July 9, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names