Q8YG64 (RPOZ_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase subunit omega
Short name=RNAP omega subunit
EC=2.7.7.6

Alternative name(s):
RNA polymerase omega subunit
Transcriptase subunit omega

Gene names

Name:	rpoZ
Ordered Locus Names:	BMEI1297

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits By similarity. HAMAP-Rule MF_00366
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_00366
Subunit structure	The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.
Sequence similarities	Belongs to the RNA polymerase subunit omega family.

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: HAMAP
Cellular_component	RNA polymerase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 133	133	DNA-directed RNA polymerase subunit omega HAMAP-Rule MF_00366		PRO_0000128922

Sequences

	Sequence		Length	Mass (Da)
	Q8YG64 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 0F6191D6B99842B0	FASTA	133	14,514
	10 20 30 40 50 60 MARVTVEDCV DKVENRFELV LLAGHRARQI SQGAPITVDR DNDKNPVVAL REIADETLSP 70 80 90 100 110 120 DDLKEDLIHS LQKHVEVDEP EAAPAQIANA AEEIAEGIAE AGEEDVVTFD RMSEEELLAG 130 IEGLVAPEKN DGF

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52478.1.
PIR	AC3414.
RefSeq	NP_540214.1. NC_003317.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI1297.
Proteomic databases
PRIDE	Q8YG64.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL52478; AAL52478; BMEI1297.
GeneID	1197008.
KEGG	bme:BMEI1297.
PATRIC	17797373. VBIBruMel146950_0505.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000245721.
KO	K03060.
OMA	KVDNRFE.
ProtClustDB	PRK00392.
Family and domain databases
Gene3D	3.90.940.10. 1 hit.
HAMAP	MF_00366. RNApol_bact_RpoZ.
InterPro	IPR003716. DNA-dir_RNA_pol_omega. IPR006110. RNA_poly_omega/K/RPABC2. IPR012293. RNAP_RPB6_omega. [Graphical view]
Pfam	PF01192. RNA_pol_Rpb6. 1 hit. [Graphical view]
SUPFAM	SSF63562. RNA_pol_omega. 1 hit.
TIGRFAMs	TIGR00690. rpoZ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPOZ_BRUME

Accession

Primary (citable) accession number: Q8YG64

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 15, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 71 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program