Q8YFW7 (Q8YFW7_BRUME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Mannose-1-phosphate guanylyltransferase EMBL AAL52576.1
EC=2.7.7.22 EMBL AAL52576.1

Submitted name:
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase EMBL EEW88708.1

Gene names

Ordered Locus Names:	BMEI1395
ORF Names:	BAWG_0816 EMBL EEW88708.1

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	474 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the mannose-6-phosphate isomerase type 2 family. RuleBase RU004190

Ontologies

Keywords
Molecular function	Isomerase EMBL EEW88708.1 Nucleotidyltransferase EMBL AAL52576.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipopolysaccharide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW mannose-1-phosphate guanylyltransferase (GDP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8YFW7 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 9AF5B92C86EF6FDC	FASTA	474	52,323
	10 20 30 40 50 60 MREMLMRPVV LAGGKGTRLW PMSRSQRPKQ FLALTGELSL FQMTLKRLSD PNRYSSPIII 70 80 90 100 110 120 TNADYRFLVA EQALECGVEL SDVILEPMAR NTAPAIAAAA LIASKDEQTL IHVVASDHNI 130 140 150 160 170 180 EINDAYFQAV DTACNAARMG RLATFGITPT EPATGFGYIE AGELEESGAC AIKRFVEKPK 190 200 210 220 230 240 EEVAREMLAA GGFYWNSGMF LFRSDVFLDE CRRYAPAVYE AAEASVATAQ RDLDFVRLNS 250 260 270 280 290 300 AEFEKAPDIS VDYAIFEKTK LASVVPSPIH WSDLGSWDAV WKESKQDPSG NVARGPVSLH 310 320 330 340 350 360 NTNNSLVLSE GVHVAVNGVD DLTIVASEDA LYVGKLSEAQ GVGTIVKALM KQPATAKLAE 370 380 390 400 410 420 EHRTIYRPWG GYTHLLSGDR LQVKRLFIKP GKQLSLQKHH HRSEHWVVVR GVAEIVIDDK 430 440 450 460 470 SLFLSENEST YISQGAIHRV SNPGKILLEL IEVQTGAYLG EDDIVRFEDD FGRV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.
[2]	"The Genome Sequence of Brucella melitensis bv. 1 str. 16M." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 16M EMBL EEW88708.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52576.1. GG703778 Genomic DNA. Translation: EEW88708.1.
PIR	AE3426.
RefSeq	NP_540312.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YFW7.
ModBase	Search...
Protein-protein interaction databases
STRING	D0B1Y6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1197106.
GenomeReviews	Gene locus BMEI1395 in contig AE008917_GR.
KEGG	bme:BMEI1395.
NMPDR	fig|224914.1.peg.1394.
PATRIC	17797156. VBIBruMel146950_0396.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG422488.
OMA	LQANEST.
PhylomeDB	Q8YFW7.
ProtClustDB	CLSK893845.
Family and domain databases
InterPro	IPR011051. Cupin_RmlC_type. IPR006375. Man1P_GuaTrfase/Man6P_Isoase. IPR001538. Man6P_isomerase-2_C. IPR005835. NTP_transferase. IPR014710. RmlC-like_jellyroll. [Graphical view]
Gene3D	G3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit.
KO	K00971.
Pfam	PF01050. MannoseP_isomer. 1 hit. PF00483. NTP_transferase. 1 hit. [Graphical view]
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
TIGRFAMs	TIGR01479. GMP_PMI. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8YFW7_BRUME

Accession

Primary (citable) accession number: Q8YFW7
Secondary accession number(s): D0B1Y6

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)