Q8YFU0 (ALLA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	BMEI1430

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP-Rule MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP-Rule MF_00616
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	allantoin catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway purine nucleobase catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Ureidoglycolate hydrolase HAMAP-Rule MF_00616		PRO_0000120544

Sequences

	Sequence		Length	Mass (Da)
	Q8YFU0 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 491CF472902AE5AF	FASTA	169	18,982
	10 20 30 40 50 60 MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARVEAA GTQTRALINI 70 80 90 100 110 120 FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 130 140 150 160 YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52611.1.
PIR	AH3430.
RefSeq	NP_540347.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YFU0.
SMR	Q8YFU0. Positions 4-159.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI1430.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL52611; AAL52611; BMEI1430.
GeneID	1197141.
KEGG	bme:BMEI1430.
PATRIC	17797105. VBIBruMel146950_0372.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000256169.
KO	K01483.
OMA	SQAFIPM.
ProtClustDB	PRK03606.
Enzyme and pathway databases
UniPathway	UPA00395; UER00656.
Family and domain databases
Gene3D	2.60.120.480. 1 hit.
HAMAP	MF_00616. Ureidogly_hydro.
InterPro	IPR011051. RmlC_Cupin. IPR007247. Ureidogly_hydro. IPR023525. Ureidogly_hydro_bac. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
PANTHER	PTHR21221. PTHR21221. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_BRUME

Accession

Primary (citable) accession number: Q8YFU0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program