Q8YFU0 (ALLA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	BMEI1430

Organism

Brucella melitensis [Complete proteome] [HAMAP]

Taxonomic identifier

29459 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	169 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616
Subunit structure	Homodimer By similarity. HAMAP MF_00616
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 169	169	Ureidoglycolate hydrolase HAMAP MF_00616		PRO_0000120544

Sequences

	Sequence		Length	Mass (Da)
	Q8YFU0-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 491CF472902AE5AF	FASTA	169	18,982
	10 20 30 40 50 60 MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARVEAA GTQTRALINI 70 80 90 100 110 120 FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 130 140 150 160 YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52611.1.
PIR	AH3430.
RefSeq	NP_540347.1.
3D structure databases
ProteinModelPortal	Q8YFU0.
SMR	Q8YFU0. Positions 4-159.
ModBase	Search...
Genome annotation databases
GeneID	1197141.
GenomeReviews	Gene locus BMEI1430 in contig AE008917_GR.
KEGG	bme:BMEI1430.
NMPDR	fig|224914.1.peg.1429.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG289179.
OMA	SQAFIPM.
PhylomeDB	Q8YFU0.
ProtClustDB	PRK03606.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI1430-MONOMER.
BRENDA	3.5.3.19. 277959.
Family and domain databases
HAMAP	MF_00616. Ureidogly_hydro. [Tree]
InterPro	IPR007247. Ureidogly_hydro. [Graphical view]
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_BRUME

Accession

Primary (citable) accession number: Q8YFU0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	March 1, 2002
Last modified:	August 10, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)