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Q8YFU0 (ALLA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ureidoglycolate lyase

EC=4.3.2.3
Alternative name(s):
Ureidoglycolatase
Gene names
Name:allA
Ordered Locus Names:BMEI1430
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length169 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source By similarity. HAMAP-Rule MF_00616

Catalytic activity

(S)-ureidoglycolate = glyoxylate + urea. HAMAP-Rule MF_00616

Cofactor

Nickel By similarity. HAMAP-Rule MF_00616

Pathway

Nitrogen metabolism; (S)-allantoin degradation. HAMAP-Rule MF_00616

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00616

Sequence similarities

Belongs to the ureidoglycolate lyase family.

Ontologies

Keywords
   Biological processPurine metabolism
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processallantoin catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

purine nucleobase metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionureidoglycolate hydrolase activity

Inferred from electronic annotation. Source: InterPro

ureidoglycolate lyase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 169169Ureidoglycolate lyase HAMAP-Rule MF_00616
PRO_0000120544

Sequences

Sequence LengthMass (Da)Tools
Q8YFU0 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 491CF472902AE5AF

FASTA16918,982
        10         20         30         40         50         60 
MQIETLTVEP LTKEAFAPFG DVIEVEGAQL RLINNGTTER YHDLARVEAA GTQTRALINI 

        70         80         90        100        110        120 
FRGQSFAAPI DIMMMERHPF GSQAFIPLNG RPFLVVVAED AGAGPARPRA FLARGDQGVN 

       130        140        150        160 
YLRNIWHHPL LALEQKSDFL VVDRAGREDN LEEYFFSDYA YRIETTQTA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008917 Genomic DNA. Translation: AAL52611.1.
PIRAH3430.
RefSeqNP_540347.1. NC_003317.1.

3D structure databases

ProteinModelPortalQ8YFU0.
SMRQ8YFU0. Positions 4-159.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEI1430.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL52611; AAL52611; BMEI1430.
GeneID1197141.
KEGGbme:BMEI1430.
PATRIC17797105. VBIBruMel146950_0372.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000256169.
KOK01483.
OMAPLNDKPY.
OrthoDBEOG6JX7JB.

Enzyme and pathway databases

UniPathwayUPA00395.

Family and domain databases

Gene3D2.60.120.480. 1 hit.
HAMAPMF_00616. Ureidogly_lyase.
InterProIPR011051. RmlC_Cupin.
IPR007247. Ureidogly_hydro.
IPR023525. Ureidogly_hydro_bac.
IPR024060. Ureidoglycolate_hydrolase_dom.
[Graphical view]
PANTHERPTHR21221. PTHR21221. 1 hit.
PfamPF04115. Ureidogly_hydro. 1 hit.
[Graphical view]
PIRSFPIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAMSSF51182. SSF51182. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALLA_BRUME
AccessionPrimary (citable) accession number: Q8YFU0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 12, 2003
Last sequence update: March 1, 2002
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names