Q8YFB4 (Q8YFB4_BRUME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Proline iminopeptidase RuleBase RU003421
EC=3.4.11.5 RuleBase RU003421

Gene names

Ordered Locus Names:

BMEI1608

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Release of N-terminal proline from a peptide. RuleBase RU003421
Sequence similarities	Belongs to the peptidase S33 family. RuleBase RU003421

Ontologies

Keywords
Molecular function	Aminopeptidase RuleBase RU003421 EMBL AAL52789.1 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	134	1	Nucleophile By similarity PIRSR PIRSR006431-1
	Active site	290	1	By similarity PIRSR PIRSR006431-1
	Active site	318	1	Proton donor By similarity PIRSR PIRSR006431-1

Sequences

	Sequence		Length	Mass (Da)
	Q8YFB4 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 2AD91587AA90EAF6	FASTA	338	38,970
	10 20 30 40 50 60 MTHHRNATGG PILPAEGNKR HFMTRNTLYP EIEPFKEEML QVSSLHRIHV EQCGNPDGKP 70 80 90 100 110 120 VIMIHGGPGG GITPTMRRLH DPKRYRIILF DQRGCGRSTP HAELRENTTW DLVADMEHIR 130 140 150 160 170 180 AHLGIDKWQV FGGSWGSTLG LAYAETHPER VSELVLRGIF MVRRFEVDWM YSNGASIIFP 190 200 210 220 230 240 DHFEAYQEHI PEAERGDMIA AYYKRLTDRD PRVQLEAARR WARWEGSVIS LLPDPARVDA 250 260 270 280 290 300 FGEDQYAIAF ARIECHYFQN RGFLESDDQL LRNVERIRHI PGVIVHGRYD ICTPFINAWQ 310 320 330 LKKMWPEADL KIVEDSGHAV TEPGIMHELI EATKRFCE

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52789.1.
PIR	AB3453.
RefSeq	NP_540525.1. NC_003317.1.
3D structure databases
HSSP	HSSP built from PDB template 1QTR based on UniProtKB O32449.
ProteinModelPortal	Q8YFB4.
SMR	Q8YFB4. Positions 26-337.
ModBase	Search...
Protein family/group databases
MEROPS	S33.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1197319.
GenomeReviews	Gene locus BMEI1608 in contig AE008917_GR.
KEGG	bme:BMEI1608.
PATRIC	17853591. VBIBruMel92729_1785.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG677789.
OMA	AELDWYY.
ProtClustDB	CLSK898486.
Family and domain databases
InterPro	IPR000073. AB_hydrolase_1. IPR005944. Pept_S33. IPR002410. Peptidase_S33. [Graphical view]
KO	K01259.
PANTHER	PTHR10992:SF12. PTHR10992:SF12. 1 hit.
Pfam	PF00561. Abhydrolase_1. 1 hit. [Graphical view]
PIRSF	PIRSF006431. Pept_S33. 1 hit.
PRINTS	PR00111. ABHYDROLASE. PR00793. PROAMNOPTASE.
TIGRFAMs	TIGR01249. Pro_imino_pep_1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8YFB4_BRUME

Accession

Primary (citable) accession number: Q8YFB4

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	December 14, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)