Q8YET3 (IHFB_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Integration host factor subunit beta
Short name=IHF-beta

Gene names

Name:	ihfB
Synonyms:	himD
Ordered Locus Names:	BMEI1794

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	94 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control By similarity. HAMAP MF_00381
Subunit structure	Heterodimer of an alpha and a beta chain By similarity. HAMAP MF_00381
Sequence similarities	Belongs to the bacterial histone-like protein family.
Sequence caution	The sequence AAL52975.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	DNA recombination Transcription Transcription regulation Translation regulation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW regulation of translation Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 94	94	Integration host factor subunit beta HAMAP MF_00381		PRO_0000105043

Sequences

	Sequence		Length	Mass (Da)
	Q8YET3 [UniParc]. Last modified June 6, 2002. Version 2. Checksum: AD0A2DBF39F9FDC1	FASTA	94	10,536
	10 20 30 40 50 60 MIKSELVQII ASRNPHLFQR DVVNIVGAVF DEITNALAEG NRVELRGFGA FSVKNRPARS 70 80 90 GRNPRTGETV DVEEKWVPFF KTGKKLRDRL NGAV

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL52975.1. Different initiation.
PIR	AD3476.
RefSeq	NP_540711.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YET3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1197505.
GenomeReviews	Gene locus BMEI1794 in contig AE008917_GR.
KEGG	bme:BMEI1794.
NMPDR	fig|224914.1.peg.1793.
PATRIC	17854000. VBIBruMel92729_1985.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG705085.
OMA	PEKYVPH.
PhylomeDB	Q8YET3.
ProtClustDB	PRK00199.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI1794-MONOMER.
Family and domain databases
HAMAP	MF_00381. IHF-beta. [Tree]
InterPro	IPR023630. DNA-bd_HU/IHF. IPR000119. Hist_DNA-bd_bac. IPR020816. Histone-like_DNA-bd_CS. IPR010992. IHF-like_DNA-bd. IPR005685. IHF_beta. [Graphical view]
Gene3D	G3DSA:4.10.520.10. Hist_DNA_bd_bac. 1 hit.
KO	K05788.
Pfam	PF00216. Bac_DNA_binding. 1 hit. [Graphical view]
PRINTS	PR01727. DNABINDINGHU.
SMART	SM00411. BHL. 1 hit. [Graphical view]
SUPFAM	SSF47729. IHF_like_DNA_bnd. 1 hit.
TIGRFAMs	TIGR00988. Hip. 1 hit.
PROSITE	PS00045. HISTONE_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IHFB_BRUME

Accession

Primary (citable) accession number: Q8YET3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 6, 2002
Last sequence update:	June 6, 2002
Last modified:	January 25, 2012
This is version 62 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program