Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8YEG1

- AROA_BRUME

UniProt

Q8YEG1 - AROA_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

3-phosphoshikimate 1-carboxyvinyltransferase

Gene

aroA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 3-phosphoshikimate 1-carboxyvinyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-KW
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-1963-MONOMER.
UniPathwayiUPA00053; UER00089.

Names & Taxonomyi

Protein namesi
Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferaseUniRule annotation (EC:2.5.1.19UniRule annotation)
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthaseUniRule annotation
Short name:
EPSP synthaseUniRule annotation
Short name:
EPSPSUniRule annotation
Gene namesi
Name:aroAUniRule annotation
Ordered Locus Names:BMEI1917
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome I

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 4504503-phosphoshikimate 1-carboxyvinyltransferasePRO_0000088233Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BMEI1917.

Structurei

3D structure databases

ProteinModelPortaliQ8YEG1.
SMRiQ8YEG1. Positions 8-447.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EPSP synthase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247371.
KOiK00800.
OMAiKRPMRRI.
OrthoDBiEOG6Z6FZ4.

Family and domain databases

Gene3Di3.65.10.10. 2 hits.
HAMAPiMF_00210. EPSP_synth.
InterProiIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
PfamiPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF000505. EPSPS. 1 hit.
SUPFAMiSSF55205. SSF55205. 1 hit.
TIGRFAMsiTIGR01356. aroA. 1 hit.
PROSITEiPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8YEG1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHSACPKPA TARHSQALTG EIRIPGDKSI SHRSFMFGGL ASGKTRITGL
60 70 80 90 100
LEGEDVINTG RAMQAMGARI RKEGDVWIIN GVGNGCLLQP EAPLDFGNAG
110 120 130 140 150
TGARLTMGLV GTYDMKTSFI GDASLSKRPM GRVLNPLREM GVQVEAAEGD
160 170 180 190 200
RMPLTLIGPR TANPIAYRVP MASAQVKSAV LLAGLNTPGV TTVIEPVMTR
210 220 230 240 250
DHTEKMLQGF GADLTVETDK DGVRHIRIVG QGKLTGQTID VPGDPSSTAF
260 270 280 290 300
PLVAALLVEG SDVTIRNVLM NPTRTGLILT LQEMGADIEI IDPRLAGGED
310 320 330 340 350
VADLRVKASK LKGVVVPPER APSMIDEYPV LAIAASFAEG ETVMDGLDEL
360 370 380 390 400
RVKESDRLAA VARGLEANGV DCTEGEMSLT VRGRPGGKGL GGGTVGTHLD
410 420 430 440 450
HRIAMSFLVM GLASEKPVTV DDSTMIATSF PEFMGMMAGL GAKIAESGAE
Length:450
Mass (Da):47,207
Last modified:June 6, 2003 - v2
Checksum:i931C4B483C162CB7
GO

Sequence cautioni

The sequence AAL53098.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL53098.1. Different initiation.
PIRiAG3491.
RefSeqiNP_540834.1. NC_003317.1.

Genome annotation databases

EnsemblBacteriaiAAL53098; AAL53098; BMEI1917.
GeneIDi1197628.
KEGGibme:BMEI1917.
PATRICi17854268. VBIBruMel92729_2119.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008917 Genomic DNA. Translation: AAL53098.1 . Different initiation.
PIRi AG3491.
RefSeqi NP_540834.1. NC_003317.1.

3D structure databases

ProteinModelPortali Q8YEG1.
SMRi Q8YEG1. Positions 8-447.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEI1917.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53098 ; AAL53098 ; BMEI1917 .
GeneIDi 1197628.
KEGGi bme:BMEI1917.
PATRICi 17854268. VBIBruMel92729_2119.

Phylogenomic databases

HOGENOMi HOG000247371.
KOi K00800.
OMAi KRPMRRI.
OrthoDBi EOG6Z6FZ4.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00089 .
BioCyci BMEL224914:GCJ0-1963-MONOMER.

Family and domain databases

Gene3Di 3.65.10.10. 2 hits.
HAMAPi MF_00210. EPSP_synth.
InterProi IPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view ]
Pfami PF00275. EPSP_synthase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000505. EPSPS. 1 hit.
SUPFAMi SSF55205. SSF55205. 1 hit.
TIGRFAMsi TIGR01356. aroA. 1 hit.
PROSITEi PS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiAROA_BRUME
AccessioniPrimary (citable) accession number: Q8YEG1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: June 6, 2003
Last modified: October 29, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3