Reviewed,
UniProtKB/Swiss-Prot Q8YEG1 (AROA_BRUME)
Last modified
November 3, 2009.
Version 47.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 3-phosphoshikimate 1-carboxyvinyltransferase EC=2.5.1.19 Alternative name(s): 5-enolpyruvylshikimate-3-phosphate synthase Short name=EPSP synthase Short name=EPSPS | ||||
| Gene names |
| ||||
| Organism | Brucella melitensis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 29459 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella |
Protein attributes
| Sequence length | 450 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210 |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210 |
| Subunit structure | Monomer By similarity. |
| Subcellular location | Cytoplasm Probable. |
| Sequence similarities | Belongs to the EPSP synthase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Cellular component | Cytoplasm |
| Molecular function | Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 450 | 450 | 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210 | PRO_0000088233 | |||
Sequences
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References
| [1] | "The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. Overbeek R.Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094 / Biotype 1. |
Cross-references
Sequence databases | |
|---|---|
| AE008917 Genomic DNA. Translation: AAL53098.1. Different initiation. | |
| PIR | AG3491. |
| RefSeq | NP_540834.1. |
3D structure databases | |
| SMR | Q8YEG1. Positions 8-447. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1197628. |
| GenomeReviews | Gene locus BMEI1917 in contig AE008917_GR. |
| KEGG | bme:BMEI1917. |
| NMPDR | fig|224914.1.peg.1916. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8YEG1. |
| OMA | NPTRIEA. |
Enzyme and pathway databases | |
| BioCyc | BMEL224914:BMEI1917-MON. |
| BRENDA | 2.5.1.19. 277959. |
Family and domain databases | |
| HAMAP | MF_00210. [Tree] |
| InterPro | IPR016228. EPSP_synthase. IPR001986. EPSP_synthase_core. IPR006264. EPSP_synthase_subgroup. [Graphical view] |
| Gene3D | G3DSA:3.65.10.10. EPSP_synthase. 1 hit. |
| Pfam | PF00275. EPSP_synthase. 1 hit. [Graphical view] |
| PIRSF | PIRSF000505. EPSPS. 1 hit. |
| ProDom | PD001867. EPSP_synth. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR01356. aroA. 1 hit. |
| PROSITE | PS00104. EPSP_SYNTHASE_1. 1 hit. PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AROA_BRUME | ||||||||
| Accession | Primary (citable) accession number: Q8YEG1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Brucella melitensis Brucella melitensis (strain 16M): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


