Q8YE23 (SECB_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-export protein secB

Gene names

Name:	secB
Ordered Locus Names:	BMEI2055

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA By similarity. HAMAP MF_00821
Subunit structure	Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00821.
Sequence similarities	Belongs to the secB family.

Ontologies

Keywords
Biological process	Protein transport Translocation Transport
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein tetramerization Inferred from electronic annotation. Source: InterPro protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 163	163	Protein-export protein secB HAMAP MF_00821		PRO_0000055354

Sequences

	Sequence		Length	Mass (Da)
	Q8YE23 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 79D31398E1690A28	FASTA	163	17,878
	10 20 30 40 50 60 MSDKAAGETK NGNGATTEPS LNILAQYVKD LSFESPGAPL SLRPREKAPS ININVNVNAN 70 80 90 100 110 120 PLSETDFDVV LTLEAKAVDG KDILFNTELV YGGVFRIQGI PQEHMLPLLF IECPRLLFPF 130 140 150 160 ARQIIADATR NGGYPPLMID PIDFAQMFQQ RMAEEQAKSA VKS

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008917 Genomic DNA. Translation: AAL53236.1.
PIR	AI3508.
RefSeq	NP_540972.1. NC_003317.1.
3D structure databases
ProteinModelPortal	Q8YE23.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1197766.
GenomeReviews	Gene locus BMEI2055 in contig AE008917_GR.
KEGG	bme:BMEI2055.
PATRIC	17795721. VBIBruMel146950_1132.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG294212.
OMA	GFPPLMI.
PhylomeDB	Q8YE23.
ProtClustDB	PRK05751.
Enzyme and pathway databases
BioCyc	BMEL224914:BMEI2055-MONOMER.
Family and domain databases
HAMAP	MF_00821. SecB. [Tree]
InterPro	IPR003708. SecB. [Graphical view]
Gene3D	G3DSA:3.10.420.10. SecB. 1 hit.
KO	K03071.
Pfam	PF02556. SecB. 1 hit. [Graphical view]
PRINTS	PR01594. SECBCHAPRONE.
SUPFAM	SSF54611. SecB. 1 hit.
TIGRFAMs	TIGR00809. SecB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SECB_BRUME

Accession

Primary (citable) accession number: Q8YE23

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program