Q8YDL2 (FLBT_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable flagellum biosynthesis repressor protein FlbT

Gene names

Name:	flbT
Ordered Locus Names:	BMEII0163

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation By similarity. HAMAP-Rule MF_00783
Sequence similarities	Belongs to the FlbT family.
Caution	Brucella species display species-specific inactivation of flagellar genes and are consequently nonmotile.

Ontologies

Keywords
Biological process	Bacterial flagellum biogenesis
Ligand	RNA-binding
Molecular function	Repressor
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	flagellum organization Inferred from electronic annotation. Source: UniProtKB-KW mRNA catabolic process Inferred from electronic annotation. Source: InterPro negative regulation of flagellum assembly Inferred from electronic annotation. Source: HAMAP
Molecular_function	mRNA 5'-UTR binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 152	152	Probable flagellum biosynthesis repressor protein FlbT HAMAP-Rule MF_00783		PRO_0000217153

Sequences

	Sequence		Length	Mass (Da)
	Q8YDL2 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 6462F5EE7D3A3151	FASTA	152	16,799
	10 20 30 40 50 60 MAANSKTAIR LSLRAGERIF INGAVLRADR KVSLELLNDA TFLLENHVLQ PEDTTTPLRQ 70 80 90 100 110 120 LYFAAQMMLI EPAMREQAGA TFAQMLKGMF ATFKDAEILN ALKLVDELVH NGRVFEALKT 130 140 150 IRAQYPREAE LMGAQPVVWP VTKSGKSAGA NP

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008918 Genomic DNA. Translation: AAL53404.1.
PIR	AI3529.
RefSeq	NP_541140.1. NC_003318.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEII0163.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL53404; AAL53404; BMEII0163.
GeneID	1197934.
KEGG	bme:BMEII0163.
PATRIC	17798315. VBIBruMel146950_1504.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000226658.
KO	K06601.
OMA	MILINPE.
ProtClustDB	PRK00794.
Family and domain databases
HAMAP	MF_00783. FlbT.
InterPro	IPR009967. Flagellum_FlbT. [Graphical view]
Pfam	PF07378. FlbT. 1 hit. [Graphical view]
PIRSF	PIRSF009533. FlbT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FLBT_BRUME

Accession

Primary (citable) accession number: Q8YDL2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program