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Q8YDJ7 (ZNUA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
High-affinity zinc uptake system protein ZnuA
Gene names
Name:znuA
Ordered Locus Names:BMEII0178
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in host cells By similarity.

Subcellular location

Periplasm By similarity.

Sequence similarities

Belongs to the bacterial solute-binding protein 9 family.

Sequence caution

The sequence AAL53419.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processIon transport
Transport
Virulence
Zinc transport
   Cellular componentPeriplasm
   DomainSignal
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpathogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

zinc ion transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 334311High-affinity zinc uptake system protein ZnuA
PRO_0000248945

Regions

Compositional bias126 – 16843His-rich

Sites

Metal binding611Zinc By similarity
Metal binding1681Zinc By similarity
Metal binding2321Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YDJ7 [UniParc].

Last modified September 5, 2006. Version 2.
Checksum: F3CAA3631569099F

FASTA33436,036
        10         20         30         40         50         60 
MKNLHSLFLA SAFLAGFCGS SLAGEREGVV VSIKPLHSIV SAVMQGVGKP KLIVQGAGSE 

        70         80         90        100        110        120 
HVYSLKPSDA EAIEHAKVIF WAGPSMETFL DKPIDTLGEG AKVVALGDAK GLTKLKFREG 

       130        140        150        160        170        180 
GPFEAHDHGH GGSHEEEHDA HGSGDHDHAA EVAEEGHEHH HHGEYDLHFW LDPQNGKILA 

       190        200        210        220        230        240 
ADIAKTLGES DPEHAAQYEK NAKAYGEKLD ALTREVAAEL KPVKDKPFIV FHDAYQYFEN 

       250        260        270        280        290        300 
RFGMKAAGSI TVSPEKAPGA ARIQQIHDKI KSLGATCVFS EPQFEPKLVK TVVDGTKART 

       310        320        330 
GVLDPLGAEL KDGPDLYPQL IRNLANSLKD CLSK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008918 Genomic DNA. Translation: AAL53419.1. Different initiation.
PIRAH3531.
RefSeqNP_541155.1. NC_003318.1.

3D structure databases

ProteinModelPortalQ8YDJ7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEII0178.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL53419; AAL53419; BMEII0178.
GeneID1197949.
KEGGbme:BMEII0178.
PATRIC17854962. VBIBruMel92729_2461.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000180311.
KOK09815.
OMAHDHDHRP.
OrthoDBEOG6PGK2R.
ProtClustDBCLSK886373.

Enzyme and pathway databases

BioCycBMEL224914:GCJ0-2286-MONOMER.

Family and domain databases

InterProIPR006127. Perip_solute-bd_prot_fam.
[Graphical view]
PfamPF01297. TroA. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ8YDJ7.

Entry information

Entry nameZNUA_BRUME
AccessionPrimary (citable) accession number: Q8YDJ7
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: November 13, 2013
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names