Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8YDJ7

- ZNUA_BRUME

UniProt

Q8YDJ7 - ZNUA_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

High-affinity zinc uptake system protein ZnuA

Gene

znuA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in host cells (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi61 – 611ZincBy similarity
Metal bindingi168 – 1681ZincBy similarity
Metal bindingi232 – 2321ZincBy similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
  2. zinc ion transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ion transport, Transport, Virulence, Zinc transport

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciBMEL224914:GCJ0-2286-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
High-affinity zinc uptake system protein ZnuA
Gene namesi
Name:znuA
Ordered Locus Names:BMEII0178
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome II

Subcellular locationi

Periplasm By similarity

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 334311High-affinity zinc uptake system protein ZnuAPRO_0000248945Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEII0178.

Structurei

3D structure databases

ProteinModelPortaliQ8YDJ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi126 – 16843His-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000180311.
KOiK09815.
OMAiKSNKDYF.
OrthoDBiEOG6PGK2R.

Family and domain databases

InterProiIPR006127. Perip_solute-bd_prot_fam.
[Graphical view]
PfamiPF01297. TroA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8YDJ7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNLHSLFLA SAFLAGFCGS SLAGEREGVV VSIKPLHSIV SAVMQGVGKP
60 70 80 90 100
KLIVQGAGSE HVYSLKPSDA EAIEHAKVIF WAGPSMETFL DKPIDTLGEG
110 120 130 140 150
AKVVALGDAK GLTKLKFREG GPFEAHDHGH GGSHEEEHDA HGSGDHDHAA
160 170 180 190 200
EVAEEGHEHH HHGEYDLHFW LDPQNGKILA ADIAKTLGES DPEHAAQYEK
210 220 230 240 250
NAKAYGEKLD ALTREVAAEL KPVKDKPFIV FHDAYQYFEN RFGMKAAGSI
260 270 280 290 300
TVSPEKAPGA ARIQQIHDKI KSLGATCVFS EPQFEPKLVK TVVDGTKART
310 320 330
GVLDPLGAEL KDGPDLYPQL IRNLANSLKD CLSK
Length:334
Mass (Da):36,036
Last modified:September 5, 2006 - v2
Checksum:iF3CAA3631569099F
GO

Sequence cautioni

The sequence AAL53419.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53419.1. Different initiation.
PIRiAH3531.
RefSeqiNP_541155.1. NC_003318.1.

Genome annotation databases

EnsemblBacteriaiAAL53419; AAL53419; BMEII0178.
GeneIDi1197949.
KEGGibme:BMEII0178.
PATRICi17854962. VBIBruMel92729_2461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53419.1 . Different initiation.
PIRi AH3531.
RefSeqi NP_541155.1. NC_003318.1.

3D structure databases

ProteinModelPortali Q8YDJ7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEII0178.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53419 ; AAL53419 ; BMEII0178 .
GeneIDi 1197949.
KEGGi bme:BMEII0178.
PATRICi 17854962. VBIBruMel92729_2461.

Phylogenomic databases

HOGENOMi HOG000180311.
KOi K09815.
OMAi KSNKDYF.
OrthoDBi EOG6PGK2R.

Enzyme and pathway databases

BioCyci BMEL224914:GCJ0-2286-MONOMER.

Miscellaneous databases

PROi Q8YDJ7.

Family and domain databases

InterProi IPR006127. Perip_solute-bd_prot_fam.
[Graphical view ]
Pfami PF01297. TroA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiZNUA_BRUME
AccessioniPrimary (citable) accession number: Q8YDJ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: October 29, 2014
This is version 73 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3