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Q8YDJ7

- ZNUA_BRUME

UniProt

Q8YDJ7 - ZNUA_BRUME

Protein

High-affinity zinc uptake system protein ZnuA

Gene

znuA

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 2 (05 Sep 2006)
      Previous versions | rss
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    Functioni

    Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in host cells By similarity.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi61 – 611ZincBy similarity
    Metal bindingi168 – 1681ZincBy similarity
    Metal bindingi232 – 2321ZincBy similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. pathogenesis Source: UniProtKB-KW
    2. zinc ion transport Source: UniProtKB-KW

    Keywords - Biological processi

    Ion transport, Transport, Virulence, Zinc transport

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciBMEL224914:GCJ0-2286-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    High-affinity zinc uptake system protein ZnuA
    Gene namesi
    Name:znuA
    Ordered Locus Names:BMEII0178
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome II

    Subcellular locationi

    Periplasm By similarity

    GO - Cellular componenti

    1. periplasmic space Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Periplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2323Sequence AnalysisAdd
    BLAST
    Chaini24 – 334311High-affinity zinc uptake system protein ZnuAPRO_0000248945Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi224914.BMEII0178.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YDJ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi126 – 16843His-richAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    HOGENOMiHOG000180311.
    KOiK09815.
    OMAiKSNKDYF.
    OrthoDBiEOG6PGK2R.

    Family and domain databases

    InterProiIPR006127. Perip_solute-bd_prot_fam.
    [Graphical view]
    PfamiPF01297. TroA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8YDJ7-1 [UniParc]FASTAAdd to Basket

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    MKNLHSLFLA SAFLAGFCGS SLAGEREGVV VSIKPLHSIV SAVMQGVGKP    50
    KLIVQGAGSE HVYSLKPSDA EAIEHAKVIF WAGPSMETFL DKPIDTLGEG 100
    AKVVALGDAK GLTKLKFREG GPFEAHDHGH GGSHEEEHDA HGSGDHDHAA 150
    EVAEEGHEHH HHGEYDLHFW LDPQNGKILA ADIAKTLGES DPEHAAQYEK 200
    NAKAYGEKLD ALTREVAAEL KPVKDKPFIV FHDAYQYFEN RFGMKAAGSI 250
    TVSPEKAPGA ARIQQIHDKI KSLGATCVFS EPQFEPKLVK TVVDGTKART 300
    GVLDPLGAEL KDGPDLYPQL IRNLANSLKD CLSK 334
    Length:334
    Mass (Da):36,036
    Last modified:September 5, 2006 - v2
    Checksum:iF3CAA3631569099F
    GO

    Sequence cautioni

    The sequence AAL53419.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53419.1. Different initiation.
    PIRiAH3531.
    RefSeqiNP_541155.1. NC_003318.1.

    Genome annotation databases

    EnsemblBacteriaiAAL53419; AAL53419; BMEII0178.
    GeneIDi1197949.
    KEGGibme:BMEII0178.
    PATRICi17854962. VBIBruMel92729_2461.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53419.1 . Different initiation.
    PIRi AH3531.
    RefSeqi NP_541155.1. NC_003318.1.

    3D structure databases

    ProteinModelPortali Q8YDJ7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEII0178.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL53419 ; AAL53419 ; BMEII0178 .
    GeneIDi 1197949.
    KEGGi bme:BMEII0178.
    PATRICi 17854962. VBIBruMel92729_2461.

    Phylogenomic databases

    HOGENOMi HOG000180311.
    KOi K09815.
    OMAi KSNKDYF.
    OrthoDBi EOG6PGK2R.

    Enzyme and pathway databases

    BioCyci BMEL224914:GCJ0-2286-MONOMER.

    Miscellaneous databases

    PROi Q8YDJ7.

    Family and domain databases

    InterProi IPR006127. Perip_solute-bd_prot_fam.
    [Graphical view ]
    Pfami PF01297. TroA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiZNUA_BRUME
    AccessioniPrimary (citable) accession number: Q8YDJ7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: September 5, 2006
    Last modified: October 1, 2014
    This is version 72 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3