Q8YDH1 (Y205_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative peptide import ATP-binding protein BMEII0205
EC=3.6.3.-

Gene names

Ordered Locus Names:

BMEII0205

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	376 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for energy coupling to the transport system By similarity.
Subunit structure	The complex is composed of two ATP-binding proteins (BMEII0205 and BMEII0206), two transmembrane proteins (BMEII0207/BMEII0208 and BMEII0209) and a solute-binding protein (BMEII0210) Probable.
Subcellular location	Cell inner membrane; Peripheral membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Peptide transport Protein transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Ligand	ATP-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC protein transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro peptide transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 376	376	Putative peptide import ATP-binding protein BMEII0205		PRO_0000290158
Regions
	Domain	64 – 314	251	ABC transporter
	Nucleotide binding	106 – 113	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q8YDH1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 42F91933A0D5058A	FASTA	376	41,202
	10 20 30 40 50 60 MPLRPALHLR TGKLRQTPTH NEPDGWAGQP LSAAAAHRGV CPMSDVMTAN RRSFLAEDGK 70 80 90 100 110 120 ETIVRTDDLV RDFDLGHRPE GGRLVLRAVD KVSLTIRRGE TLGLVGESGS GKSTIGRMLV 130 140 150 160 170 180 GLLPYTSGNI ELFGQKIEPR AKAAAWKPLR RRVQFVFQDP HAALNPRMRV GTAIAEPLDV 190 200 210 220 230 240 AGNLTRKERS ARVDELMELV GLPTSFARRF PHEFSGGQRQ RIVIARALAL NPEILVCDEA 250 260 270 280 290 300 VASLDVSMQA QIVNLLKDLQ DQLGLSHLFI AHDLAVVRAV SHRVAVLYAG QIVETGPRTA 310 320 330 340 350 360 LYSDPLHPYS RALLDSVPRA RRGAPRSIIA GEVPSLLNKP KGCAFCPRCP KAMDICRDVP 370 PPLRVIGDRE VACHLY

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008918 Genomic DNA. Translation: AAL53446.1.
PIR	AC3535.
RefSeq	NP_541182.1. NC_003318.1.
3D structure databases
ProteinModelPortal	Q8YDH1.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEII0205.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL53446; AAL53446; BMEII0205.
GeneID	1197976.
KEGG	bme:BMEII0205.
PATRIC	17855036. VBIBruMel92729_2491.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K02032.
OMA	KMYYFTN.
ProtClustDB	CLSK898743.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR010066. Oligo_ATP-bd_C. IPR013563. Oligopep_ABC_C. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. PF08352. oligo_HPY. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
TIGRFAMs	TIGR01727. oligo_HPY. 1 hit.
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y205_BRUME

Accession

Primary (citable) accession number: Q8YDH1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 12, 2007
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program