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Q8YDC6

- GLK_BRUME

UniProt

Q8YDC6 - GLK_BRUME

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Protein

Glucokinase

Gene

glk

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 236ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:BMEII0251
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome II

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 343343GlucokinasePRO_0000215121Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224914.BMEII0251.

Structurei

3D structure databases

ProteinModelPortaliQ8YDC6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000274469.
KOiK00845.
OMAiDKAPHSA.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YDC6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQAIIDAEQS FKFPVLVGDI GGTNARFSIL VDSNAEPKEF PVLQTADYAT
60 70 80 90 100
IDEAIQHAIL DQTAIQPRSV ILAVAGPVDG DEIDLTNCDW VVRPKKMIAD
110 120 130 140 150
LGFEDVTVLN DFEAQALAVV SLEGHHMEQI GGKPEEAVAT RVVLGPGTGL
160 170 180 190 200
GVAGLVCTRH AWVPVPGEGG HIDIGPRTER DYQIFPHIER IEGRVTGEQI
210 220 230 240 250
LSGRGLRNLY LGICAADKIT PTLETPVDIT SAGLDGSNPQ AAETLDLFAT
260 270 280 290 300
YLGRLAGDLA LIFMAHGGVY LSGGIPVRIL SALKAGSFRA AFEDKAPNKA
310 320 330 340
IMRDIPVRVI TYQLAALTGL SAFARTPSRF EVSTEGRRWR MRR
Length:343
Mass (Da):36,919
Last modified:June 6, 2002 - v2
Checksum:i8984E115FE71B9EE
GO

Sequence cautioni

The sequence AAL53492.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53492.1. Different initiation.
PIRiAI3540.
RefSeqiNP_541228.1. NC_003318.1.

Genome annotation databases

EnsemblBacteriaiAAL53492; AAL53492; BMEII0251.
GeneIDi1198022.
KEGGibme:BMEII0251.
PATRICi17800683. VBIBruMel146950_2672.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53492.1 . Different initiation.
PIRi AI3540.
RefSeqi NP_541228.1. NC_003318.1.

3D structure databases

ProteinModelPortali Q8YDC6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEII0251.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53492 ; AAL53492 ; BMEII0251 .
GeneIDi 1198022.
KEGGi bme:BMEII0251.
PATRICi 17800683. VBIBruMel146950_2672.

Phylogenomic databases

HOGENOMi HOG000274469.
KOi K00845.
OMAi DKAPHSA.
OrthoDBi EOG64BQ47.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiGLK_BRUME
AccessioniPrimary (citable) accession number: Q8YDC6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: June 6, 2002
Last modified: October 29, 2014
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3