Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8YDA3

- YIDC_BRUME

UniProt

Q8YDA3 - YIDC_BRUME

Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 2 (21 Nov 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.UniRule annotation

    GO - Biological processi

    1. protein insertion into membrane Source: InterPro
    2. protein transport Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chaperone

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Membrane protein insertase YidCUniRule annotation
    Alternative name(s):
    Foldase YidCUniRule annotation
    Membrane integrase YidCUniRule annotation
    Membrane protein YidCUniRule annotation
    Gene namesi
    Name:yidCUniRule annotation
    Ordered Locus Names:BMEII0275
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome II

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 610610Membrane protein insertase YidCPRO_0000124694Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.UniRule annotation

    Protein-protein interaction databases

    STRINGi224914.BMEII0275.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei7 – 2721HelicalUniRule annotationAdd
    BLAST
    Transmembranei358 – 37821HelicalUniRule annotationAdd
    BLAST
    Transmembranei387 – 40721HelicalUniRule annotationAdd
    BLAST
    Transmembranei458 – 47821HelicalUniRule annotationAdd
    BLAST
    Transmembranei510 – 53021HelicalUniRule annotationAdd
    BLAST
    Transmembranei546 – 56621HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000101821.
    KOiK03217.
    OMAiFVTIEMR.
    OrthoDBiEOG6X6RF2.

    Family and domain databases

    HAMAPiMF_01810. YidC_type1.
    InterProiIPR019998. Membr_insert_YidC.
    IPR028055. Membr_insert_YidC/Oxa1_C.
    IPR028053. Membr_insert_YidC_N.
    IPR001708. Membrane_insert_OXA1/ALB3/YidC.
    [Graphical view]
    PANTHERiPTHR12428. PTHR12428. 1 hit.
    PfamiPF02096. 60KD_IMP. 1 hit.
    PF14849. YidC_periplas. 1 hit.
    [Graphical view]
    PRINTSiPR00701. 60KDINNERMP.
    PR01900. YIDCPROTEIN.
    TIGRFAMsiTIGR03593. yidC_nterm. 1 hit.
    TIGR03592. yidC_oxa1_cterm. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8YDA3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MENKRNFFIT IALSILILAL WQVFYLGPKT EAQREQARIE EQQRQAQQAA    50
    QNRQASSSTG DTPQMPANPD SIPGQGDTKA AGAPLTRDAA IAQSPRIEID 100
    TPSLRGSINL TGARLDDLYL KKYHETVSDK SPEIELLAPS SLKQGYFVEL 150
    GFTGNDATGA VPGPNTVWVV EGNNKLTPST PVTLTYTNDK NLTFKRVISV 200
    DDAYMFTVDD TIINNGGSTV SLASYGRVTR FNQPEHASAT YVLHEGLIGV 250
    MGQDGLQEIK YAKIEDNKDI SFKDVIGGWV GITDKYWAAT LIPPQDEKFT 300
    GRFSHFTNDR PRYQSDLLSA PLTVAPGQSQ KIQNRVFAGA KVVNTIQNYE 350
    TKYHIKQFDL LIDWGWFYFI TKPMFYLIDW IYKFTGNFGV AILVVTVLLK 400
    ALFFPLANKS YKSMARMKLM QPKMTEIREK YADDKMKQQQ AMMELYKREK 450
    INPLAGCWPV LVQIPVFFAL YKVLYVTIEM RHAPFFGWIQ DLAAPDPTSI 500
    FNLFGLLPYT VPHFLMIGVW PIIMGIIMFL QMRMNPTPPD PTQAAIFTWM 550
    PIIFTFMLAS FPAGLVIYWA WNNTLSIIQQ SVIMKRQGVK IELFDNLKGL 600
    FRRKPKEANK 610
    Length:610
    Mass (Da):69,051
    Last modified:November 21, 2003 - v2
    Checksum:iFB13B7D1B5C1652D
    GO

    Sequence cautioni

    The sequence AAL53516.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53516.1. Different initiation.
    PIRiAI3543.
    RefSeqiNP_541252.2. NC_003318.1.

    Genome annotation databases

    EnsemblBacteriaiAAL53516; AAL53516; BMEII0275.
    GeneIDi1198046.
    KEGGibme:BMEII0275.
    PATRICi17855188. VBIBruMel92729_2565.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53516.1 . Different initiation.
    PIRi AI3543.
    RefSeqi NP_541252.2. NC_003318.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEII0275.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL53516 ; AAL53516 ; BMEII0275 .
    GeneIDi 1198046.
    KEGGi bme:BMEII0275.
    PATRICi 17855188. VBIBruMel92729_2565.

    Phylogenomic databases

    HOGENOMi HOG000101821.
    KOi K03217.
    OMAi FVTIEMR.
    OrthoDBi EOG6X6RF2.

    Family and domain databases

    HAMAPi MF_01810. YidC_type1.
    InterProi IPR019998. Membr_insert_YidC.
    IPR028055. Membr_insert_YidC/Oxa1_C.
    IPR028053. Membr_insert_YidC_N.
    IPR001708. Membrane_insert_OXA1/ALB3/YidC.
    [Graphical view ]
    PANTHERi PTHR12428. PTHR12428. 1 hit.
    Pfami PF02096. 60KD_IMP. 1 hit.
    PF14849. YidC_periplas. 1 hit.
    [Graphical view ]
    PRINTSi PR00701. 60KDINNERMP.
    PR01900. YIDCPROTEIN.
    TIGRFAMsi TIGR03593. yidC_nterm. 1 hit.
    TIGR03592. yidC_oxa1_cterm. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiYIDC_BRUME
    AccessioniPrimary (citable) accession number: Q8YDA3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 21, 2003
    Last sequence update: November 21, 2003
    Last modified: October 1, 2014
    This is version 67 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3