Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8YDA3

- YIDC_BRUME

UniProt

Q8YDA3 - YIDC_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.UniRule annotation

GO - Biological processi

  1. protein insertion into membrane Source: InterPro
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidCUniRule annotation
Alternative name(s):
Foldase YidCUniRule annotation
Membrane integrase YidCUniRule annotation
Membrane protein YidCUniRule annotation
Gene namesi
Name:yidCUniRule annotation
Ordered Locus Names:BMEII0275
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome II

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 610610Membrane protein insertase YidCPRO_0000124694Add
BLAST

Interactioni

Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.UniRule annotation

Protein-protein interaction databases

STRINGi224914.BMEII0275.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721HelicalUniRule annotationAdd
BLAST
Transmembranei358 – 37821HelicalUniRule annotationAdd
BLAST
Transmembranei387 – 40721HelicalUniRule annotationAdd
BLAST
Transmembranei458 – 47821HelicalUniRule annotationAdd
BLAST
Transmembranei510 – 53021HelicalUniRule annotationAdd
BLAST
Transmembranei546 – 56621HelicalUniRule annotationAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000101821.
KOiK03217.
OMAiFVTIEMR.
OrthoDBiEOG6X6RF2.

Family and domain databases

HAMAPiMF_01810. YidC_type1.
InterProiIPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view]
PRINTSiPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsiTIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YDA3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENKRNFFIT IALSILILAL WQVFYLGPKT EAQREQARIE EQQRQAQQAA
60 70 80 90 100
QNRQASSSTG DTPQMPANPD SIPGQGDTKA AGAPLTRDAA IAQSPRIEID
110 120 130 140 150
TPSLRGSINL TGARLDDLYL KKYHETVSDK SPEIELLAPS SLKQGYFVEL
160 170 180 190 200
GFTGNDATGA VPGPNTVWVV EGNNKLTPST PVTLTYTNDK NLTFKRVISV
210 220 230 240 250
DDAYMFTVDD TIINNGGSTV SLASYGRVTR FNQPEHASAT YVLHEGLIGV
260 270 280 290 300
MGQDGLQEIK YAKIEDNKDI SFKDVIGGWV GITDKYWAAT LIPPQDEKFT
310 320 330 340 350
GRFSHFTNDR PRYQSDLLSA PLTVAPGQSQ KIQNRVFAGA KVVNTIQNYE
360 370 380 390 400
TKYHIKQFDL LIDWGWFYFI TKPMFYLIDW IYKFTGNFGV AILVVTVLLK
410 420 430 440 450
ALFFPLANKS YKSMARMKLM QPKMTEIREK YADDKMKQQQ AMMELYKREK
460 470 480 490 500
INPLAGCWPV LVQIPVFFAL YKVLYVTIEM RHAPFFGWIQ DLAAPDPTSI
510 520 530 540 550
FNLFGLLPYT VPHFLMIGVW PIIMGIIMFL QMRMNPTPPD PTQAAIFTWM
560 570 580 590 600
PIIFTFMLAS FPAGLVIYWA WNNTLSIIQQ SVIMKRQGVK IELFDNLKGL
610
FRRKPKEANK
Length:610
Mass (Da):69,051
Last modified:November 21, 2003 - v2
Checksum:iFB13B7D1B5C1652D
GO

Sequence cautioni

The sequence AAL53516.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53516.1. Different initiation.
PIRiAI3543.
RefSeqiNP_541252.2. NC_003318.1.

Genome annotation databases

EnsemblBacteriaiAAL53516; AAL53516; BMEII0275.
GeneIDi1198046.
KEGGibme:BMEII0275.
PATRICi17855188. VBIBruMel92729_2565.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53516.1 . Different initiation.
PIRi AI3543.
RefSeqi NP_541252.2. NC_003318.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEII0275.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53516 ; AAL53516 ; BMEII0275 .
GeneIDi 1198046.
KEGGi bme:BMEII0275.
PATRICi 17855188. VBIBruMel92729_2565.

Phylogenomic databases

HOGENOMi HOG000101821.
KOi K03217.
OMAi FVTIEMR.
OrthoDBi EOG6X6RF2.

Family and domain databases

HAMAPi MF_01810. YidC_type1.
InterProi IPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view ]
PANTHERi PTHR12428. PTHR12428. 1 hit.
Pfami PF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view ]
PRINTSi PR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsi TIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiYIDC_BRUME
AccessioniPrimary (citable) accession number: Q8YDA3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: November 21, 2003
Last modified: October 29, 2014
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3