SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8YDA3

- YIDC_BRUME

UniProt

Q8YDA3 - YIDC_BRUME

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Membrane protein insertase YidC
Gene
yidC, BMEII0275
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins By similarity.UniRule annotation

GO - Biological processi

  1. protein insertion into membrane Source: InterPro
  2. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane protein insertase YidC
Alternative name(s):
Foldase YidC
Membrane integrase YidC
Membrane protein YidC
Gene namesi
Name:yidC
Ordered Locus Names:BMEII0275
OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Taxonomic identifieri224914 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000419: Chromosome II

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2721Helical; Reviewed prediction
Add
BLAST
Transmembranei358 – 37821Helical; Reviewed prediction
Add
BLAST
Transmembranei387 – 40721Helical; Reviewed prediction
Add
BLAST
Transmembranei458 – 47821Helical; Reviewed prediction
Add
BLAST
Transmembranei510 – 53021Helical; Reviewed prediction
Add
BLAST
Transmembranei546 – 56621Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 610610Membrane protein insertase YidCUniRule annotation
PRO_0000124694Add
BLAST

Interactioni

Subunit structurei

Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.

Protein-protein interaction databases

STRINGi224914.BMEII0275.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000101821.
KOiK03217.
OMAiFVTIEMR.
OrthoDBiEOG6X6RF2.

Family and domain databases

HAMAPiMF_01810. YidC_type1.
InterProiIPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view]
PANTHERiPTHR12428. PTHR12428. 1 hit.
PfamiPF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view]
PRINTSiPR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsiTIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8YDA3-1 [UniParc]FASTAAdd to Basket

« Hide

MENKRNFFIT IALSILILAL WQVFYLGPKT EAQREQARIE EQQRQAQQAA    50
QNRQASSSTG DTPQMPANPD SIPGQGDTKA AGAPLTRDAA IAQSPRIEID 100
TPSLRGSINL TGARLDDLYL KKYHETVSDK SPEIELLAPS SLKQGYFVEL 150
GFTGNDATGA VPGPNTVWVV EGNNKLTPST PVTLTYTNDK NLTFKRVISV 200
DDAYMFTVDD TIINNGGSTV SLASYGRVTR FNQPEHASAT YVLHEGLIGV 250
MGQDGLQEIK YAKIEDNKDI SFKDVIGGWV GITDKYWAAT LIPPQDEKFT 300
GRFSHFTNDR PRYQSDLLSA PLTVAPGQSQ KIQNRVFAGA KVVNTIQNYE 350
TKYHIKQFDL LIDWGWFYFI TKPMFYLIDW IYKFTGNFGV AILVVTVLLK 400
ALFFPLANKS YKSMARMKLM QPKMTEIREK YADDKMKQQQ AMMELYKREK 450
INPLAGCWPV LVQIPVFFAL YKVLYVTIEM RHAPFFGWIQ DLAAPDPTSI 500
FNLFGLLPYT VPHFLMIGVW PIIMGIIMFL QMRMNPTPPD PTQAAIFTWM 550
PIIFTFMLAS FPAGLVIYWA WNNTLSIIQQ SVIMKRQGVK IELFDNLKGL 600
FRRKPKEANK 610
Length:610
Mass (Da):69,051
Last modified:November 21, 2003 - v2
Checksum:iFB13B7D1B5C1652D
GO

Sequence cautioni

The sequence AAL53516.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53516.1. Different initiation.
PIRiAI3543.
RefSeqiNP_541252.2. NC_003318.1.

Genome annotation databases

EnsemblBacteriaiAAL53516; AAL53516; BMEII0275.
GeneIDi1198046.
KEGGibme:BMEII0275.
PATRICi17855188. VBIBruMel92729_2565.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE008918 Genomic DNA. Translation: AAL53516.1 . Different initiation.
PIRi AI3543.
RefSeqi NP_541252.2. NC_003318.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224914.BMEII0275.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL53516 ; AAL53516 ; BMEII0275 .
GeneIDi 1198046.
KEGGi bme:BMEII0275.
PATRICi 17855188. VBIBruMel92729_2565.

Phylogenomic databases

HOGENOMi HOG000101821.
KOi K03217.
OMAi FVTIEMR.
OrthoDBi EOG6X6RF2.

Family and domain databases

HAMAPi MF_01810. YidC_type1.
InterProi IPR019998. Membr_insert_YidC.
IPR028055. Membr_insert_YidC/Oxa1_C.
IPR028053. Membr_insert_YidC_N.
IPR001708. Membrane_insert_OXA1/ALB3/YidC.
[Graphical view ]
PANTHERi PTHR12428. PTHR12428. 1 hit.
Pfami PF02096. 60KD_IMP. 1 hit.
PF14849. YidC_periplas. 1 hit.
[Graphical view ]
PRINTSi PR00701. 60KDINNERMP.
PR01900. YIDCPROTEIN.
TIGRFAMsi TIGR03593. yidC_nterm. 1 hit.
TIGR03592. yidC_oxa1_cterm. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 16M / ATCC 23456 / NCTC 10094.

Entry informationi

Entry nameiYIDC_BRUME
AccessioniPrimary (citable) accession number: Q8YDA3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 21, 2003
Last sequence update: November 21, 2003
Last modified: May 14, 2014
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella melitensis
    Brucella melitensis (strain 16M): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi