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Q8YD40

- METN_BRUME

UniProt

Q8YD40 - METN_BRUME

Protein

Methionine import ATP-binding protein MetN

Gene

metN

Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi63 – 708ATPUniRule annotation

    GO - Molecular functioni

    1. amino acid-transporting ATPase activity Source: UniProtKB-HAMAP
    2. ATP binding Source: UniProtKB-HAMAP
    3. methionine transmembrane transporter activity Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Amino-acid transport, Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBMEL224914:GCJ0-2456-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Methionine import ATP-binding protein MetNUniRule annotation (EC:3.6.3.-UniRule annotation)
    Gene namesi
    Name:metNUniRule annotation
    Ordered Locus Names:BMEII0337
    OrganismiBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
    Taxonomic identifieri224914 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
    ProteomesiUP000000419: Chromosome II

    Subcellular locationi

    Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation

    GO - Cellular componenti

    1. ATP-binding cassette (ABC) transporter complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 369369Methionine import ATP-binding protein MetNPRO_0000270259Add
    BLAST

    Interactioni

    Subunit structurei

    The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).UniRule annotation

    Protein-protein interaction databases

    STRINGi224914.BMEII0337.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8YD40.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini31 – 266236ABC transporterUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation
    Contains 1 ABC transporter domain.UniRule annotation

    Phylogenomic databases

    KOiK02071.
    OMAiVEEGQVW.
    OrthoDBiEOG6T7N3V.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR003593. AAA+_ATPase.
    IPR026253. ABC_MetN.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR017908. ABC_transprt_methionine_MetN_C.
    IPR018449. NIL_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR24220:SF186. PTHR24220:SF186. 1 hit.
    PfamiPF00005. ABC_tran. 1 hit.
    PF09383. NIL. 1 hit.
    [Graphical view]
    SMARTiSM00382. AAA. 1 hit.
    SM00930. NIL. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51264. METN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8YD40-1 [UniParc]FASTAAdd to Basket

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    MQHAAVCSGT SRHRRTTVTI EKPPATSAPI VEMKDVRRMF GETAAINGVS    50
    LSVARGEILG IIGRSGAGKS TLIRCVNGLE KPDTGSIHIE GREITSLDED 100
    ALRPVRRRIG MVFQHFNLLS AKTAAQNIAL PLKIAGMPKA ERIKRVAELL 150
    ELVGLSDKAS HYPAQLSGGQ KQRVGIARAL AAEPAVLLSD EATSALDPET 200
    TQSILALLKD INAKLGLTIL LITHEMDVIR RIADRVIVLD HGLIAEEGPV 250
    WKVFANPQSP VTQSMLQVLT PELPAIWRNR LEKKGDQAIL RVKLSGMAAK 300
    GAFFNDVAAA TSLAPQLIHG GMDTIQGEPV GTLFIGLPAE DKTKLKAAIG 350
    YLNTHADATE VLGYVSGNA 369
    Length:369
    Mass (Da):39,445
    Last modified:March 1, 2002 - v1
    Checksum:i0E42048280DB72DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53579.1.
    PIRiAH3551.
    RefSeqiNP_541315.1. NC_003318.1.
    WP_002967208.1. NC_003318.1.

    Genome annotation databases

    EnsemblBacteriaiAAL53579; AAL53579; BMEII0337.
    GeneIDi1198109.
    KEGGibme:BMEII0337.
    PATRICi17855329. VBIBruMel92729_2633.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE008918 Genomic DNA. Translation: AAL53579.1 .
    PIRi AH3551.
    RefSeqi NP_541315.1. NC_003318.1.
    WP_002967208.1. NC_003318.1.

    3D structure databases

    ProteinModelPortali Q8YD40.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224914.BMEII0337.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL53579 ; AAL53579 ; BMEII0337 .
    GeneIDi 1198109.
    KEGGi bme:BMEII0337.
    PATRICi 17855329. VBIBruMel92729_2633.

    Phylogenomic databases

    KOi K02071.
    OMAi VEEGQVW.
    OrthoDBi EOG6T7N3V.

    Enzyme and pathway databases

    BioCyci BMEL224914:GCJ0-2456-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR003593. AAA+_ATPase.
    IPR026253. ABC_MetN.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR017908. ABC_transprt_methionine_MetN_C.
    IPR018449. NIL_domain.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR24220:SF186. PTHR24220:SF186. 1 hit.
    Pfami PF00005. ABC_tran. 1 hit.
    PF09383. NIL. 1 hit.
    [Graphical view ]
    SMARTi SM00382. AAA. 1 hit.
    SM00930. NIL. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 1 hit.
    PS51264. METN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 16M / ATCC 23456 / NCTC 10094.

    Entry informationi

    Entry nameiMETN_BRUME
    AccessioniPrimary (citable) accession number: Q8YD40
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 9, 2007
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Brucella melitensis
      Brucella melitensis (strain 16M): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3