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Q8YD40 (METN_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Methionine import ATP-binding protein MetN

EC=3.6.3.-
Gene names
Name:metN
Ordered Locus Names:BMEII0337
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system By similarity.

Subunit structure

The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ) Potential.

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity.

Sequence similarities

Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]

Contains 1 ABC transporter domain.

Ontologies

Keywords
   Biological processAmino-acid transport
Transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   LigandATP-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentplasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

methionine transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 369369Methionine import ATP-binding protein MetN
PRO_0000270259

Regions

Domain31 – 266236ABC transporter
Nucleotide binding63 – 708ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q8YD40 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 0E42048280DB72DD

FASTA36939,445
        10         20         30         40         50         60 
MQHAAVCSGT SRHRRTTVTI EKPPATSAPI VEMKDVRRMF GETAAINGVS LSVARGEILG 

        70         80         90        100        110        120 
IIGRSGAGKS TLIRCVNGLE KPDTGSIHIE GREITSLDED ALRPVRRRIG MVFQHFNLLS 

       130        140        150        160        170        180 
AKTAAQNIAL PLKIAGMPKA ERIKRVAELL ELVGLSDKAS HYPAQLSGGQ KQRVGIARAL 

       190        200        210        220        230        240 
AAEPAVLLSD EATSALDPET TQSILALLKD INAKLGLTIL LITHEMDVIR RIADRVIVLD 

       250        260        270        280        290        300 
HGLIAEEGPV WKVFANPQSP VTQSMLQVLT PELPAIWRNR LEKKGDQAIL RVKLSGMAAK 

       310        320        330        340        350        360 
GAFFNDVAAA TSLAPQLIHG GMDTIQGEPV GTLFIGLPAE DKTKLKAAIG YLNTHADATE 


VLGYVSGNA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008918 Genomic DNA. Translation: AAL53579.1.
PIRAH3551.
RefSeqNP_541315.1. NC_003318.1.

3D structure databases

ProteinModelPortalQ8YD40.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEII0337.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL53579; AAL53579; BMEII0337.
GeneID1198109.
KEGGbme:BMEII0337.
PATRIC17855329. VBIBruMel92729_2633.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02071.
OMAHGGIDHI.
OrthoDBEOG6T7N3V.
ProtClustDBCLSK864122.

Enzyme and pathway databases

BioCycBMEL224914:GCJ0-2456-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR003593. AAA+_ATPase.
IPR026253. ABC_MetN.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017908. ABC_transprt_methionine_MetN_C.
IPR018449. NIL_domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERPTHR24220:SF186. PTHR24220:SF186. 1 hit.
PfamPF00005. ABC_tran. 1 hit.
PF09383. NIL. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
SM00930. NIL. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
PS51264. METN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMETN_BRUME
AccessionPrimary (citable) accession number: Q8YD40
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: March 1, 2002
Last modified: April 16, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names