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Q8YD04 (DADA_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit

EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:BMEII0373
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP-Rule MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP-Rule MF_01202

Cofactor

FAD By similarity. HAMAP-Rule MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-amino acid catabolic process

Inferred from electronic annotation. Source: InterPro

alanine catabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416D-amino acid dehydrogenase small subunit HAMAP-Rule MF_01202
PRO_0000166128

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
Q8YD04 [UniParc].

Last modified March 5, 2002. Version 1.
Checksum: 7480382FF5614CA2

FASTA41645,110
        10         20         30         40         50         60 
MQITILGSGV IGVTTAYYLA KLGHEVTVID REEGPALETS FANAGQVSPG YASPWAAPGI 

        70         80         90        100        110        120 
PLKAAKWLFQ KHAPLILRLT TDPVQYRWLL QMLANCTDSR YKINKTRMVR VAEYSRDCLI 

       130        140        150        160        170        180 
ELRKDTGIEY DQRSQGTLQL FREQYQLDGI GKDIEVLRQD GVPFEVLDRD GCVNVEPALA 

       190        200        210        220        230        240 
HAKDKFVGGL RLPNDETGDC FKFTNALAKI AEGLGVKFRF GVNIKSLLMS GGKISGVETS 

       250        260        270        280        290        300 
EGIVTAERYV VALGSYTPAL IKALGLNAPI YPVKGYSITA PIVDESRAPV STVLDESYKI 

       310        320        330        340        350        360 
AITRLGDRIR VGGMAEVSGF TDDLPAARRA TLDLSVTDLF PGGDLKAATF WSGLRPMTPD 

       370        380        390        400        410 
STPIIGGTRY DNLFINAGHG TLGWTMACGS GRLLADLISG NKADIRADDL GIARYN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008918 Genomic DNA. Translation: AAL53615.1.
PIRAD3556.
RefSeqNP_541351.1. NC_003318.1.

3D structure databases

ProteinModelPortalQ8YD04.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEII0373.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL53615; AAL53615; BMEII0373.
GeneID1198145.
KEGGbme:BMEII0373.
PATRIC17800390. VBIBruMel146950_2527.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000217450.
KOK00285.
OMANDLYPRG.
OrthoDBEOG6KMBD9.
ProtClustDBPRK00711.

Family and domain databases

HAMAPMF_01202. DadA.
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_BRUME
AccessionPrimary (citable) accession number: Q8YD04
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: February 19, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names