Q8YCE3 (FDHD_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein FdhD homolog

Gene names

Name:	fdhD
Ordered Locus Names:	BMEII0588

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	269 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Necessary for formate dehydrogenase activity By similarity. HAMAP-Rule MF_00187
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00187.
Sequence similarities	Belongs to the FdhD family.

Ontologies

Keywords
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell formate dehydrogenase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	formate dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 269	269	Protein FdhD homolog HAMAP-Rule MF_00187		PRO_0000152894

Sequences

	Sequence		Length	Mass (Da)
	Q8YCE3 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 33117EBD4F459A99	FASTA	269	28,876
	10 20 30 40 50 60 MTNQKISRDV HHLAHRMSGF QESSRIVPEE APIAMSYNGT TQAVMMATPG DLEDFAIGFS 70 80 90 100 110 120 LTENIVTRIE EIEALDIVAF ESGIDIQMKL AKQPEQRLSA RRRFMAGQVG CGLCGIDSIE 130 140 150 160 170 180 QALRPLHPLE ECSTTFTTRD IAAAVASLGA AQALNAKTHA THGAGFFRPG EGLFAVREDI 190 200 210 220 230 240 GRHNALDKLI GAVAREGLLA EEGIVAITSR VSVEMVQKAV MLGVPVLAAI SAPTALAIRT 250 260 AEAANLTLVA LVRDEEFDIY THCGRIIEG

References

[1]

"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008918 Genomic DNA. Translation: AAL53830.1.
PIR	AC3583.
RefSeq	NP_541566.1. NC_003318.1.
3D structure databases
ProteinModelPortal	Q8YCE3.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEII0588.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL53830; AAL53830; BMEII0588.
GeneID	1198360.
KEGG	bme:BMEII0588.
PATRIC	17799924. VBIBruMel146950_2296.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000079468.
KO	K02379.
OMA	YVANEVR.
ProtClustDB	PRK00724.
Family and domain databases
HAMAP	MF_00187. FdhD.
InterPro	IPR003786. Formate_DH_FdhD_su. [Graphical view]
Pfam	PF02634. FdhD-NarQ. 1 hit. [Graphical view]
PIRSF	PIRSF015626. FdhD. 1 hit.
TIGRFAMs	TIGR00129. fdhD_narQ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FDHD_BRUME

Accession

Primary (citable) accession number: Q8YCE3

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 31, 2003
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program