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Q8YC29 (RIMO_BRUME) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal protein S12 methylthiotransferase RimO

Short name=S12 MTTase
Short name=S12 methylthiotransferase
EC=2.-.-.-
Alternative name(s):
Ribosome maturation factor RimO
Gene names
Name:rimO
Ordered Locus Names:BMEII0703
OrganismBrucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]
Taxonomic identifier224914 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 By similarity. HAMAP-Rule MF_01865

Cofactor

Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity.

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01865.

Sequence similarities

Belongs to the methylthiotransferase family. RimO subfamily.

Contains 1 MTTase N-terminal domain.

Contains 1 TRAM domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 437437Ribosomal protein S12 methylthiotransferase RimO HAMAP-Rule MF_01865
PRO_0000374724

Regions

Domain4 – 114111MTTase N-terminal
Domain372 – 43766TRAM

Sites

Metal binding131Iron-sulfur (4Fe-4S) By similarity
Metal binding491Iron-sulfur (4Fe-4S) By similarity
Metal binding781Iron-sulfur (4Fe-4S) By similarity
Metal binding1451Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Metal binding1491Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Metal binding1521Iron-sulfur (4Fe-4S-S-AdoMet) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8YC29 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 530B6217DDF24656

FASTA43748,774
        10         20         30         40         50         60 
MSAPRVSFVS LGCPKALVDS ERIITGLRSE GYEISRKHDG ADLVIVNTCG FLDSARDESL 

        70         80         90        100        110        120 
EAIGLALNEN GKVIVTGCLG AEPDVIRERH PNVLAITGPQ AYESVMNAVH EVAPPAHDPF 

       130        140        150        160        170        180 
VDLVPPQGVK LTPRHYAYLK ISEGCSNRCS FCIIPALRGD LVSRPINEVL REAEKLVQAG 

       190        200        210        220        230        240 
VKEILVISQD TSAYGLDIKY QEAMWQDRTV RTKFLDLSRE LGEMGVWVRM HYVYPYPHVD 

       250        260        270        280        290        300 
EVIPLMAEGK ILPYLDIPFQ HASPAVLKNM RRPAHQEKTS RRIQAWRETC PDLAVRSTFI 

       310        320        330        340        350        360 
VGYPGETEED FQMLLDWLDE AKIERAGCFK YEAVKGAKAN DLGLEQVPEE VKEARWHRFM 

       370        380        390        400        410        420 
AKQQQISTNL LKKKVGKRLP VIIDEANGTI GKGRTRYDAP EIDGSVHISS RRPLRVGDIV 

       430 
TVKIEASDAY DLHGTAV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE008918 Genomic DNA. Translation: AAL53945.1.
PIRAF3597.
RefSeqNP_541681.1. NC_003318.1.

3D structure databases

ProteinModelPortalQ8YC29.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224914.BMEII0703.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL53945; AAL53945; BMEII0703.
GeneID1198475.
KEGGbme:BMEII0703.
PATRIC17799660. VBIBruMel146950_2167.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000224766.
KOK14441.
OMAMRRFGST.
OrthoDBEOG6P5ZD8.
ProtClustDBPRK14862.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
3.80.30.20. 1 hit.
HAMAPMF_01865. MTTase_RimO.
InterProIPR006638. Elp3/MiaB/NifB.
IPR023970. MeThioTfrase/rSAM.
IPR005839. Methylthiotransferase.
IPR020612. Methylthiotransferase_CS.
IPR013848. Methylthiotransferase_N.
IPR012340. NA-bd_OB-fold.
IPR005840. Ribosomal_S12_MeSTrfase_RimO.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
IPR002792. TRAM_dom.
[Graphical view]
PANTHERPTHR11918. PTHR11918. 1 hit.
PfamPF04055. Radical_SAM. 1 hit.
PF00919. UPF0004. 1 hit.
[Graphical view]
SMARTSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00089. TIGR00089. 1 hit.
TIGR01125. TIGR01125. 1 hit.
PROSITEPS51449. MTTASE_N. 1 hit.
PS01278. MTTASE_RADICAL. 1 hit.
PS50926. TRAM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRIMO_BRUME
AccessionPrimary (citable) accession number: Q8YC29
Entry history
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: March 1, 2002
Last modified: February 19, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Brucella melitensis

Brucella melitensis (strain 16M): entries and gene names