Q8YC08 (Q8YC08_BRUME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Udp-glucose 6-dehydrogenase EMBL AAL53969.1
EC=1.1.1.22 EMBL AAL53969.1

Gene names

Ordered Locus Names:	BMEII0727
ORF Names:	BAWG_1854 EMBL EEW87375.1

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length	474 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL AAL53969.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro UDP-glucose 6-dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8YC08 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 45C23EA8B7373548	FASTA	474	51,331
	10 20 30 40 50 60 MKIAVIGTGY VGLVSGTCFA AWGHEVVCGD KNARKIAVLE RGILPIYEPG LDELVERNCA 70 80 90 100 110 120 EGRLRFTCNL AEAVRGAEMV FIAVGTPPRA GHGDADLSFV YMAARELAPL IDENAVVVVK 130 140 150 160 170 180 STVPVGTGDI VQKLIGSVRR AGTFSVASNP EFLREGVAIR DFLYPDRVVI GVEDERARKA 190 200 210 220 230 240 LLDLYGTPLK EQKTPIVVTQ RRTSELIKYA ANAFLATKIT FINELADLCE HVGSDVSQLA 250 260 270 280 290 300 LGIGLDKRIG ESFLNAGPGY GGSCFPKDTL ALLRTAQDHG VALRIVEETV TANEARKRRM 310 320 330 340 350 360 ALKVLDALGG DVEGLTIAVM GLTFKPDTDD MRDAPSVPLI ETLQRFGARI RAYDPIGAEN 370 380 390 400 410 420 ARNILSDVEL CDDPYECVRA ADAMVVITEW DSIRRLDLSR VRQAMRQPVL IDLRNAYEPN 430 440 450 460 470 VAENLGFRVS AVGRAATARH ETSIKDALSL LASRSRRADS AEELVPEGGG SNDL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed: 11756688] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.
[2]	"The Genome Sequence of Brucella melitensis bv. 1 str. 16M." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Whatmore A.M., Perrett L.L., O'Callaghan D., Nusbaum C., Galagan J., Birren B. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 16M EMBL EEW87375.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE008918 Genomic DNA. Translation: AAL53969.1. GG703779 Genomic DNA. Translation: EEW87375.1.
PIR	AF3600.
RefSeq	NP_541705.1. NC_003318.1.
3D structure databases
HSSP	HSSP built from PDB template 1MFZ based on UniProtKB P11759.
ProteinModelPortal	Q8YC08.
ModBase	Search...
Protein-protein interaction databases
STRING	D0B6Y3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1198499.
GenomeReviews	Gene locus BMEII0727 in contig AE008918_GR.
KEGG	bme:BMEII0727.
NMPDR	fig|224914.1.peg.2787.
PATRIC	17799618. VBIBruMel146950_2147.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG400967.
OMA	LCEKIGA.
PhylomeDB	Q8YC08.
ProtClustDB	CLSK898922.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR021157. Cyt_c1_TM_anchor_C. IPR016040. NAD(P)-bd_dom. IPR017476. Nucleotide_sugar_DH. IPR014027. UDP-Glc/GDP-Man_DH_C. IPR014026. UDP-Glc/GDP-Man_DH_dimer. IPR001732. UDP-Glc/GDP-Man_DH_N. [Graphical view]
Gene3D	G3DSA:1.20.5.100. Cyt_c1_TM_anchor_C. 1 hit. G3DSA:3.40.50.720. NAD(P)-bd. 2 hits.
KO	K00012.
Pfam	PF00984. UDPG_MGDP_dh. 1 hit. PF03720. UDPG_MGDP_dh_C. 1 hit. PF03721. UDPG_MGDP_dh_N. 1 hit. [Graphical view]
PIRSF	PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMART	SM00984. UDPG_MGDP_dh_C. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit. SSF52413. UDP-Glc/GDP-Man_DH_C. 1 hit.
TIGRFAMs	TIGR03026. NDP-sugDHase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q8YC08_BRUME

Accession

Primary (citable) accession number: Q8YC08
Secondary accession number(s): D0B6Y3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)