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Q8Y9N4 (AROD_LISMO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate dehydratase
Short name=3-dehydroquinase
EC=4.2.1.10
Alternative name(s):
Type I DHQase
Gene names
Name:aroD
Ordered Locus Names:lmo0491
OrganismListeria monocytogenes
Taxonomic identifier1639 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length252 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP MF_00214

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP MF_00214

Subunit structure

Homodimer By similarity. HAMAP MF_00214

Sequence similarities

Belongs to the type-I 3-dehydroquinase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   LigandSchiff base
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular function3-dehydroquinate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2522523-dehydroquinate dehydratase HAMAP MF_00214
PRO_0000138801

Sites

Active site1431Proton acceptor By similarity
Active site1701Schiff-base intermediate with substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8Y9N4 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: E2D8549460FBBCE5

FASTA25227,476
        10         20         30         40         50         60 
MNKVVVKNVT FGEGAPKICV PMVGKTVAAL KEEAEMLQTI DLDVVEWRVD FFEDVKDLAK 

        70         80         90        100        110        120 
VEAALGEIRA ILPETPILFT FRSAKEGGEL AVSDEFYFEL NETLAGTGKI DLVDVELFNE 

       130        140        150        160        170        180 
EADVLRLIET AHKNNVKVVM SNHDFDKTPA KEEIVSRLTR MEALGADLPK IAVMPKSAGD 

       190        200        210        220        230        240 
VLTLLDATNT VFEKANQPII TMSMAGTGVI SRLAGEVFGS AMTFGAAKKA SAPGQIDVNE 

       250 
LRHVLDLLHK QF

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL591975 Genomic DNA. Translation: CAC98570.1.
PIRAD1136.
RefSeqNP_464019.1. NC_003210.1.

3D structure databases

ProteinModelPortalQ8Y9N4.
SMRQ8Y9N4. Positions 1-250.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID985226.
GenomeReviewsGene locus lmo0491 in contig AL591824_GR.
KEGGlmo:lmo0491.
PATRIC20310049. VBILisMon69206_0510.

Organism-specific databases

GenoListLMO0491.

Phylogenomic databases

HOGENOMHBG732926.
OMAIAKIAVM.
ProtClustDBPRK02412.

Enzyme and pathway databases

BioCycLMON169963:LMO0491-MONOMER.

Family and domain databases

HAMAPMF_00214. AroD.
[Tree]
InterProIPR018508. 3-dehydroquinate_DH_AS.
IPR013785. Aldolase_TIM.
IPR001381. DHquinase_I.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK03785.
PfamPF01487. DHquinase_I. 1 hit.
[Graphical view]
TIGRFAMsTIGR01093. AroD. 1 hit.
PROSITEPS01028. DEHYDROQUINASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROD_LISMO
AccessionPrimary (citable) accession number: Q8Y9N4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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