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Q8Y8D7 (PPNK1_LISMO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 1
Short name=Poly(P)/ATP NAD kinase 1
EC=2.7.1.23
Gene names
Name:ppnK1
Ordered Locus Names:lmo0968
OrganismListeria monocytogenes
Taxonomic identifier1639 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP MF_00361

Cofactor

Divalent metal ions By similarity. HAMAP MF_00361

Subcellular location

Cytoplasm By similarity HAMAP MF_00361.

Sequence similarities

Belongs to the NAD kinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
NAD
NADP
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

NAD+ kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 264264Probable inorganic polyphosphate/ATP-NAD kinase 1 HAMAP MF_00361
PRO_0000120632

Secondary structure

1 ............................................... 264
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q8Y8D7 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 00E0BCC4CAD30653

FASTA26429,933
        10         20         30         40         50         60 
MKYMITSKGD EKSDLLRLNM IAGFGEYDME YDDVEPEIVI SIGGDGTFLS AFHQYEERLD 

        70         80         90        100        110        120 
EIAFIGIHTG HLGFYADWRP AEADKLVKLL AKGEYQKVSY PLLKTTVKYG IGKKEATYLA 

       130        140        150        160        170        180 
LNESTVKSSG GPFVVDVVIN DIHFERFRGD GLCMSTPSGT TAYNKSLGGA LMHPSIEAMQ 

       190        200        210        220        230        240 
LTEMASINNR VYRTIGSPLV FPKHHVVSLQ PVNDKDFQIS VDHLSILHRD VQEIRYEVSA 

       250        260 
KKIHFARFRS FPFWRRVHDS FIED

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL591977 Genomic DNA. Translation: CAC99046.1.
PIRAH1195.
RefSeqNP_464493.1. NC_003210.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2I1WX-ray2.34A/B/C/D1-264[»]
2I29X-ray2.10A1-264[»]
2I2AX-ray2.10A1-264[»]
2I2BX-ray2.10A1-264[»]
2I2CX-ray1.85A1-264[»]
2I2DX-ray2.22A1-264[»]
2I2EX-ray2.20A1-264[»]
2I2FX-ray1.90A1-264[»]
2Q5FX-ray1.90A1-264[»]
ProteinModelPortalQ8Y8D7.
SMRQ8Y8D7. Positions 1-264.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID986453.
GenomeReviewsGene locus lmo0968 in contig AL591824_GR.
KEGGlmo:lmo0968.
PATRIC20311034. VBILisMon69206_0995.

Organism-specific databases

GenoListLMO0968.

Phylogenomic databases

HOGENOMHBG314020.
OMATISFANC.
ProtClustDBPRK04885.

Enzyme and pathway databases

BioCycLMON169963:LMO0968-MONOMER.

Family and domain databases

HAMAPMF_00361. NAD_kinase.
[Tree]
InterProIPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017438. ATP-NAD_kinase_PpnK-typ_a/b.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. polyP/ATP_NADK_prd.
[Graphical view]
Gene3DG3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KOK00858.
PANTHERPTHR20275. ATP_NADK. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPNK1_LISMO
AccessionPrimary (citable) accession number: Q8Y8D7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2002
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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