Reviewed, UniProtKB/Swiss-Prot Q8Y7V1 (ACKA2_LISMO)

Names and origin

Protein names

Recommended name:
    Acetate kinase 2
    EC=2.7.2.1
Alternative name(s):
    Acetokinase 2

Gene names

Name:	ackA2
Ordered Locus Names:	lmo1168

Organism

Listeria monocytogenes [Complete proteome] [HAMAP]

Taxonomic identifier

1639 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 397	397	Acetate kinase 2 HAMAP MF_00020		PRO_0000107580

Sequences

	Sequence		Length	Mass (Da)
	Q8Y7V1-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 6E295A59A5FD5C5B	FASTA	397	43,133
	10 20 30 40 50 60 MHKIMAINAG SSSLKFQIFT MPGEEVLVKG LIERIGLPDA IFNMSFQNEK IKETRAINDH 70 80 90 100 110 120 GKAVEILLEQ LKAHQVINDL SEITGVGHRV AHGGEDFVTS CVVTDEVVKG IEAVTNLAPL 130 140 150 160 170 180 HNPANIIGIK TFRELLPNAV SVAVFDTAFH QTIPQENFLY ALPYELYEKH HIRKYGFHGT 190 200 210 220 230 240 SHKYVAGKAA EVLEKPLEKL KIISCHLGNG ASVCAIEAGK SVNTSMGFTP NAGLMMGTRS 250 260 270 280 290 300 GTIDATIIPY LVDELGYSLD EVMHMMSNES GVLGVSGISS DFRDIEIAAK EGNSRALLTL 310 320 330 340 350 360 RMFTGQICNY IGAYASAMNG CDALLFTAGV GENSPLIRQM VTEQLSYLGV TCHVTKNNAG 370 380 390 DMIISNDNEA VKVCIIPTNE ELMIARDVEK YAKQTIG

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed: 11679669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-679 / EGD-e / Serovar 1/2a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591978 Genomic DNA. Translation: CAC99246.1.
PIR	AH1220.
RefSeq	NP_464693.1.
3D structure databases
SMR	Q8Y7V1. Positions 3-393.
ModBase	Search...
Genome annotation databases
GeneID	986132.
KEGG	lmo:lmo1168.
Organism-specific databases
ListiList	LMO01168.
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285863.
OMA	WRYYAEL.
Enzyme and pathway databases
BioCyc	LMON169963:LMO1168-MONOMER.
BRENDA	2.7.2.1. 96770.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA2_LISMO

Accession

Primary (citable) accession number: Q8Y7V1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	March 1, 2002
Last modified:	February 9, 2010
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)